Abstract
When liver metastases from colorectal carcinoma are detected, it is the surgeon’s responsibility to decide whether or not the patient is a candidate for resection. Although long-term survival after resection is far from optimal, the relegation of patients to nonresective treatment means denying them the only chance for cure currently available. Many studies [1–5] have used regional or systemic chemotherapy for metastatic disease to the liver, but all have failed to demonstrate cure or even significant improvement in longterm survival. When isolated disease involving the liver is documented, surgical resection has the potential of being curative, and selected symptomatic patients may also obtain maximal palliation from resection.
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References
Kemeny N, Daly J, Reichman B, Geller N, Botet J, Oderman P. 1987. Intrahepatic or systemic infusion of fluorodeoxyuridine in patients with liver metastases from colorectal carcinoma: A randomized trial. Ann Intern Med 107:459–465.
Martin JK Jr., O’Connell MJ, Wieand HS, Fitzgibbons RJ Jr., Mailliard JA, Rubin J, Nagorney DM, Tschetter LK, Krook JE. 1990. Intra-arterial floxuridine vs. systemic fluorouracil for hepatic metastases from colorectal cancer: A randomized trial. Arch Surg 125:1022–1027.
Nobile MT, Vidili MG, Sertoli MR, Venturini M, Simoni G, Civalleri D, Bertoglio S, Percivale P, Torelli P, Spagliardi E, Rosso R. 1991. Intrahepatic Epidoxorubicin in metastatic and primary liver tumours: A phase II study. Anticancer Res 11:861–864.
Sterchi JM, Richards F, White DR, Muss HB, Cooper MR, Jackson DV, Spurr CL, Capizzi RL, Cruz J, Zekan PJ. 1989. Chemoinfusion of the hepatic artery for metastases to the liver. Surg Gynecol Obstet 168:291–295.
Wagman LD, Kemeny N, Leong L, Terz JJ, Hill LR, Beatty JD, Kokal WA, Riihimaki DU. 1990. A prospective, randomized evaluation of the treatment of colorectal cancer metastatic to the liver. J Clin Oncol 8:1885–1893.
Greenway B. 1988. Hepatic metastases from colorectal cancer: Resection or not. Br J Surg 75:513–519.
Hughes KS, Sugarbaker PH. 1987. Resection of the liver for metastatic solid tumors. In: SA Rosenberg (ed): Surgical Treatment of Metastatic Cancer. Philadelphia: JB Lippincott, pp 125–164.
Hughes KS, Sugarbaker PH. 1991. Hepatic resection using ultrasonic fragmentation. In: M Braverman (ed): Surgical Technology International. London: Century Press, pp 89–96.
Lise M, Da Pian PP, Nitti D, Pilati PL, Prevaldi C. 1990. Colorectal metastases to the liver: Present status of management. Dis Colon Rectum 33:688–694.
Petrelli NJ, Conte CC. 1990. Avoiding complications of hepatic resection. Infect Surg 9:25–30.
Steele G Jr., Bleday R, Mayer RJ, Linblad A, Petrelli N, Weaver D. 1991. A prospective evaluation of hepatic resection for colorectal carcinoma metastases to the liver: Gastrointestinal tumor study group protocol 6584. J Clin Oncol 9:1105–1112.
Registry of Hepatic Metastases. 1988. Resection of the liver for colorectal carcinoma metastases: A multi-institutional study of indications for resection. Surgery 103:278–288.
Benjamin IS, Blumgart LH. 1988. Hepatic resection for liver metastases. Dig Dis 6:40–51.
Hughes KS, Rossi RL. 1992. Colorectal cancer metastatic to the liver: Resection. In: J Cameron (ed): Current Surgical Therapy, 4th ed. St. Louis, MO: Mosby-Yearbook, pp 1–5.
Fantini GA, DeCosse JJ. 1990. Surveillance strategies after resection of carcinoma of the colon and rectum. Surg Gynecol Obstet 171:267–273.
Mäkelä J, Haukipuro K, Laitinen S, Kairaluoma MI. 1989. Surgical treatment of recurrent colorectal cancer: Five-year follow-up. Arch Surg 124:1029–1032.
Sugarbaker PH, Gianola FJ, Dwyer A, Neuman NR. 1987. A simplified plan for follow-up of patients with colon and rectal cancer supported by prospective studies of laboratory and radiologic test results. Surgery 102:79–87.
Griffith KD, Sugarbaker PH, Chang AE. 1990. Repeat hepatic resections for colorectal metastases. Surgery 107:101–104.
Stone MD, Cady B, Jenkins RL, McDermott WV, Steele GD Jr. 1990. Surgical therapy for recurrent liver metastases from colorectal cancer. Arch Surg 125:718–721.
Cahan WG, Castro EB, Hajdu SI. 1974. Proceedings: The significance of a solitary lung shadow in patients with colon carcinoma. Cancer 33:414–421.
Hughes KS, Simon R, Songhorabedi S, Adson MA, Ilstrup DM, Fortner JG, Maclean BJ, Foster JH, Daly JM, Fitzherbert D. 1986. Hepatic metastases registry: Resection of the liver for colorectal carcinoma metastases: A multi-institutional study of patterns of recurrence. Surgery 100:278–284.
Hughes KS, Scheele J, Sugarbaker PH. 1989. Surgery for colorectal cancer metastatic to the liver: Optimizing the results of treatment. Surg Clin North Am 69:339–359.
Foster RS Jr., Costanza MC, Foster JC, Wanner MC, Foster CB. 1985. Adverse relationship between blood transfusions and survival after colectomy for colon cancer. Cancer 55:1195–1201.
Francis DM, Judson RT. 1987. Blood transfusion and recurrence of cancer of the colon and rectum. Br J Surg 74:26–30.
Voogt PJ, van de Velde CJ, Brand A, Hermans J, Stijnen T, Bloem R, Leer JW, Zwaveling A, van Rood JJ. 1987. Perioperative blood transfusion and cancer prognosis: Different effects of blood transfusion on prognosis of colon and breast cancer patients. Cancer 59:836–843.
Sickle-Santanello BJ, O’Dwyer PJ, Mojzisik C, Tuttle SE, Hinkle GH, Rousseau M, Schlom J, Colcher D, Thurston MD, Nieroda C. 1987. Radioimmunoguided surgery using the monoclonal antibody B72.3 in colorectal tumors. Dis Colon Rectum 30:761–764.
Vogt P, Raab B, Ringe B, Pichlmayer R. 1991. Resection of synchronous liver metastases from colorectal cancer. World J Surg 15:62–67.
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© 1994 Springer Science+Business Media Dordrecht
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Asbun, H.J., Tsao, J.I., Hughes, K.S. (1994). Resection of hepatic metastases from colorectal carcinoma. In: Sugarbaker, P.H. (eds) Hepatobiliary Cancer. Cancer Treatment and Research, vol 69. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2604-9_4
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DOI: https://doi.org/10.1007/978-1-4615-2604-9_4
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