Skip to main content

Resection of hepatic metastases from colorectal carcinoma

The Registry Data

  • Chapter
Hepatobiliary Cancer

Part of the book series: Cancer Treatment and Research ((CTAR,volume 69))

Abstract

When liver metastases from colorectal carcinoma are detected, it is the surgeon’s responsibility to decide whether or not the patient is a candidate for resection. Although long-term survival after resection is far from optimal, the relegation of patients to nonresective treatment means denying them the only chance for cure currently available. Many studies [1–5] have used regional or systemic chemotherapy for metastatic disease to the liver, but all have failed to demonstrate cure or even significant improvement in longterm survival. When isolated disease involving the liver is documented, surgical resection has the potential of being curative, and selected symptomatic patients may also obtain maximal palliation from resection.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 259.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 329.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Kemeny N, Daly J, Reichman B, Geller N, Botet J, Oderman P. 1987. Intrahepatic or systemic infusion of fluorodeoxyuridine in patients with liver metastases from colorectal carcinoma: A randomized trial. Ann Intern Med 107:459–465.

    PubMed  CAS  Google Scholar 

  2. Martin JK Jr., O’Connell MJ, Wieand HS, Fitzgibbons RJ Jr., Mailliard JA, Rubin J, Nagorney DM, Tschetter LK, Krook JE. 1990. Intra-arterial floxuridine vs. systemic fluorouracil for hepatic metastases from colorectal cancer: A randomized trial. Arch Surg 125:1022–1027.

    Article  PubMed  Google Scholar 

  3. Nobile MT, Vidili MG, Sertoli MR, Venturini M, Simoni G, Civalleri D, Bertoglio S, Percivale P, Torelli P, Spagliardi E, Rosso R. 1991. Intrahepatic Epidoxorubicin in metastatic and primary liver tumours: A phase II study. Anticancer Res 11:861–864.

    PubMed  CAS  Google Scholar 

  4. Sterchi JM, Richards F, White DR, Muss HB, Cooper MR, Jackson DV, Spurr CL, Capizzi RL, Cruz J, Zekan PJ. 1989. Chemoinfusion of the hepatic artery for metastases to the liver. Surg Gynecol Obstet 168:291–295.

    PubMed  CAS  Google Scholar 

  5. Wagman LD, Kemeny N, Leong L, Terz JJ, Hill LR, Beatty JD, Kokal WA, Riihimaki DU. 1990. A prospective, randomized evaluation of the treatment of colorectal cancer metastatic to the liver. J Clin Oncol 8:1885–1893.

    PubMed  CAS  Google Scholar 

  6. Greenway B. 1988. Hepatic metastases from colorectal cancer: Resection or not. Br J Surg 75:513–519.

    Article  PubMed  CAS  Google Scholar 

  7. Hughes KS, Sugarbaker PH. 1987. Resection of the liver for metastatic solid tumors. In: SA Rosenberg (ed): Surgical Treatment of Metastatic Cancer. Philadelphia: JB Lippincott, pp 125–164.

    Google Scholar 

  8. Hughes KS, Sugarbaker PH. 1991. Hepatic resection using ultrasonic fragmentation. In: M Braverman (ed): Surgical Technology International. London: Century Press, pp 89–96.

    Google Scholar 

  9. Lise M, Da Pian PP, Nitti D, Pilati PL, Prevaldi C. 1990. Colorectal metastases to the liver: Present status of management. Dis Colon Rectum 33:688–694.

    Article  PubMed  CAS  Google Scholar 

  10. Petrelli NJ, Conte CC. 1990. Avoiding complications of hepatic resection. Infect Surg 9:25–30.

    Google Scholar 

  11. Steele G Jr., Bleday R, Mayer RJ, Linblad A, Petrelli N, Weaver D. 1991. A prospective evaluation of hepatic resection for colorectal carcinoma metastases to the liver: Gastrointestinal tumor study group protocol 6584. J Clin Oncol 9:1105–1112.

    PubMed  Google Scholar 

  12. Registry of Hepatic Metastases. 1988. Resection of the liver for colorectal carcinoma metastases: A multi-institutional study of indications for resection. Surgery 103:278–288.

    Google Scholar 

  13. Benjamin IS, Blumgart LH. 1988. Hepatic resection for liver metastases. Dig Dis 6:40–51.

    Article  PubMed  CAS  Google Scholar 

  14. Hughes KS, Rossi RL. 1992. Colorectal cancer metastatic to the liver: Resection. In: J Cameron (ed): Current Surgical Therapy, 4th ed. St. Louis, MO: Mosby-Yearbook, pp 1–5.

    Google Scholar 

  15. Fantini GA, DeCosse JJ. 1990. Surveillance strategies after resection of carcinoma of the colon and rectum. Surg Gynecol Obstet 171:267–273.

    PubMed  CAS  Google Scholar 

  16. Mäkelä J, Haukipuro K, Laitinen S, Kairaluoma MI. 1989. Surgical treatment of recurrent colorectal cancer: Five-year follow-up. Arch Surg 124:1029–1032.

    Article  PubMed  Google Scholar 

  17. Sugarbaker PH, Gianola FJ, Dwyer A, Neuman NR. 1987. A simplified plan for follow-up of patients with colon and rectal cancer supported by prospective studies of laboratory and radiologic test results. Surgery 102:79–87.

    PubMed  CAS  Google Scholar 

  18. Griffith KD, Sugarbaker PH, Chang AE. 1990. Repeat hepatic resections for colorectal metastases. Surgery 107:101–104.

    PubMed  CAS  Google Scholar 

  19. Stone MD, Cady B, Jenkins RL, McDermott WV, Steele GD Jr. 1990. Surgical therapy for recurrent liver metastases from colorectal cancer. Arch Surg 125:718–721.

    Article  PubMed  CAS  Google Scholar 

  20. Cahan WG, Castro EB, Hajdu SI. 1974. Proceedings: The significance of a solitary lung shadow in patients with colon carcinoma. Cancer 33:414–421.

    Article  PubMed  CAS  Google Scholar 

  21. Hughes KS, Simon R, Songhorabedi S, Adson MA, Ilstrup DM, Fortner JG, Maclean BJ, Foster JH, Daly JM, Fitzherbert D. 1986. Hepatic metastases registry: Resection of the liver for colorectal carcinoma metastases: A multi-institutional study of patterns of recurrence. Surgery 100:278–284.

    PubMed  CAS  Google Scholar 

  22. Hughes KS, Scheele J, Sugarbaker PH. 1989. Surgery for colorectal cancer metastatic to the liver: Optimizing the results of treatment. Surg Clin North Am 69:339–359.

    PubMed  CAS  Google Scholar 

  23. Foster RS Jr., Costanza MC, Foster JC, Wanner MC, Foster CB. 1985. Adverse relationship between blood transfusions and survival after colectomy for colon cancer. Cancer 55:1195–1201.

    Article  PubMed  Google Scholar 

  24. Francis DM, Judson RT. 1987. Blood transfusion and recurrence of cancer of the colon and rectum. Br J Surg 74:26–30.

    Article  PubMed  CAS  Google Scholar 

  25. Voogt PJ, van de Velde CJ, Brand A, Hermans J, Stijnen T, Bloem R, Leer JW, Zwaveling A, van Rood JJ. 1987. Perioperative blood transfusion and cancer prognosis: Different effects of blood transfusion on prognosis of colon and breast cancer patients. Cancer 59:836–843.

    Article  PubMed  CAS  Google Scholar 

  26. Sickle-Santanello BJ, O’Dwyer PJ, Mojzisik C, Tuttle SE, Hinkle GH, Rousseau M, Schlom J, Colcher D, Thurston MD, Nieroda C. 1987. Radioimmunoguided surgery using the monoclonal antibody B72.3 in colorectal tumors. Dis Colon Rectum 30:761–764.

    Article  PubMed  CAS  Google Scholar 

  27. Vogt P, Raab B, Ringe B, Pichlmayer R. 1991. Resection of synchronous liver metastases from colorectal cancer. World J Surg 15:62–67.

    Article  PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1994 Springer Science+Business Media Dordrecht

About this chapter

Cite this chapter

Asbun, H.J., Tsao, J.I., Hughes, K.S. (1994). Resection of hepatic metastases from colorectal carcinoma. In: Sugarbaker, P.H. (eds) Hepatobiliary Cancer. Cancer Treatment and Research, vol 69. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2604-9_4

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-2604-9_4

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6115-2

  • Online ISBN: 978-1-4615-2604-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics