Abstract
Uncontrolled studies have shown that mean serum urate levels are higher in female patients with gout than in gouty male patients (1–5) and that daily uric acid excretion is similar (4) or lower (3, 5) in the former than in the latter. These findings prompted the hypothesis that female patients with primary gout have a more defective tubular transport of uric acid than gouty male patients (3). In this prospective study, carried out under controlled conditions, we examined purine metabolism in female patients with primary gout. In addition, we investigated whether there are sex-related differences in purine metabolism among patients with primary gout.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Kuzell WC, Schaffarzick RW, Naugler WE, et al. Some observations on 520 gouty patients. J Chron Dis 1955; 2:645–669.
Meyes OL, Monteagudo FSE. A comparison of gout in men and women. A 10-year experience. S Afr Med J 1986; 70:721–723.
Puig JG, Michán AD, Jiménez ML, et al. Female Gout. Clinical spectrum and uric acid metabolism. Arch Intern Med 1991; 151:726–732.
Borg EJT, Rasker JJ. Gout in the elderly, a separate entity? Ann Rheum Dis 1987; 46:72–76.
Delbarre F, Braun S, Saint-Georges-Chaumet F. La goutte fémenine. Analyse de quarante observations. Sem Hop Paris 1967; 44:623–633.
Puig JG, Mateos FA, Jiménez ML, Ramos TH. Renal excretion of hypoxanthine and xanthine in primary gout. Am J Med 1988; 85:533–537.
Turner RE, Frank MJ, Van Ausdal D, Bollet AJ. Some aspects of the epidemiology of gout: Sex and race incidence. Arch Intern Med 1960; 106:400–404.
Lally EW, Ho G Jr, Kaplan SR. The clinical spectrum of gouty arthritis in women. Arch Intern Med 1986; 146:2221–2225.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1995 Springer Science+Business Media New York
About this chapter
Cite this chapter
Puig, J.G. et al. (1995). Purine Metabolism in Female Patients with Primary Gout. In: Sahota, A., Taylor, M.W. (eds) Purine and Pyrimidine Metabolism in Man VIII. Advances in Experimental Medicine and Biology, vol 370. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2584-4_17
Download citation
DOI: https://doi.org/10.1007/978-1-4615-2584-4_17
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-6105-3
Online ISBN: 978-1-4615-2584-4
eBook Packages: Springer Book Archive