Electrotonic Coupling between Carotid Body Glomus Cells

  • L. Monti-Bloch
  • Veronica Abudara
  • C. Eyzaguirre
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 360)

Abstract

The carotid body detects chemical changes in the blood such as PO2, PCO2 and pH, and generates afferent discharges in the carotid nerve. During stimulation, the glomus cells release endogenous substances (ACh, catecholamines, and neuropeptides) toward the carotid nerve terminals. To understand how secretion occurs, we have studied the electric connections between glomus cells at rest and during activity elicited by ‘natural’ stimuli, or the transmitters (Monti-Bloch et al., 1990, 1993). In other secretory organs, adjoining cells are electrically coupled and they uncouple (fully or partially) during secretion (for refs. see Bennett & Spray, 1985; Hertzberg & Johnson, 1988; Bennett et al., 1991).

Keywords

Permeability Dopamine Nicotine Acidity Cyanide 

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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • L. Monti-Bloch
    • 1
    • 2
  • Veronica Abudara
    • 1
    • 2
  • C. Eyzaguirre
    • 1
  1. 1.Department of PhysiologyUniversity of Utah School of MedicineSalt Lake CityUSA
  2. 2.Department of Physiology, Facultad de MedicinaUniversidad de la RepublicaMontevideoUruguay

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