Urolithiasis 2 pp 243-243 | Cite as

Anticalculogenic Properties of Scoparia dulcis Linn

  • P. J. Alphonsa
  • S. Sindhu
  • V. V. Nair
  • J. Kurien
  • P. Koshy
  • Y. M. Fazil Marickar

Abstract

Various plant preparations have been used for treatment of urinary stone disease, but their efficacy has not been proved. This paper attempts to scientifically study the anticalculogenic property of one such medicinal plant — Scoparia dulcis Linn. The plant extracts were prepared in acetone, petroleum ether and chloroform in concentrations of 20 mg%, 40 mg% & 80 mg% respectively. The inhibitory effects of these plant extracts were studied in calcium oxalate crystal growth in silica gel medium. The different test agents (drug in concentrations of 500 mg and 1 g/100 g rat weight), standard (hydrochlorothiazide 0.25 mg/100 g rat weight) and control (normal saline 0.91% – 2.5 mL/100 g rat weight) were administered orally to male Wistar albino rats. The urine output was recorded at 5 hours and 24 hours to study the diuretic property. Another group of rats was administered the drug in the above concentrations daily for one month and the blood was collected for biochemical estimations and compared with controls.

Keywords

Acetone Petroleum Chloroform Oxalate Hydrochlorothiazide 

Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • P. J. Alphonsa
    • 1
  • S. Sindhu
  • V. V. Nair
    • 1
  • J. Kurien
    • 1
  • P. Koshy
    • 2
  • Y. M. Fazil Marickar
  1. 1.Dept of Dravya Guna VijnanAyurveda CollegeTrivandrumIndia
  2. 2.RRLTrivandrum & Department of SurgeryMedical College HospitalTrivandrumIndia

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