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Urolithiasis 2 pp 193-195 | Cite as

Urinary Glycosaminoglycans Differ in their Calcium Oxalate Crystallization Activities

  • M. D. I. Gohel
  • D. K. Y. Shum

Abstract

Various studies have indicated that urinary macromolecules exhibit diverse activities towards calcium oxalate crystallization1, 2. One group of these macromolecules, the glycosaminoglycans (GAGs), has been shown to affect calcium oxalate crystallization3, 4. Our interest in GAGs stems from previous evidence that urinary polyanions exhibit differences towards crystallization of urinary calcium oxalate between normal controls and stone-formers5 and further to this, Reference standard GAGs (obtained from non-urinary sources) appear to behave differently from urinary GAGs6. The present study indicates that urinary GAG classes from normals and stone formers influence crystallization differently, though electrophoretically they appear similar.

Keywords

Heparan Sulphate Calcium Oxalate Calcium Oxalate Crystal Uronic Acid Content Barium Acetate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • M. D. I. Gohel
    • 1
  • D. K. Y. Shum
    • 1
  1. 1.Dept. of Biochemistry, Faculty of MedicineThe University of Hong KongHong Kong

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