The Value of Repeated Analyses of 24 Hour Urine in Recurrent Calcium Urolithiasis
Samples (n=441) of 24 h urine of 49 recurrent calcium stone formers (with a mean of 6.3 episodes of stone formation or passing at the time of first examination) with a mean follow-up period of 80.4 months were retrospectively analyed. Patients with hyperparathyroidism, renal tubular acidosis or hyperuricaemia were not included in the study. Evaluating the first two samples (with or without calcium load), which were taken for classifying metabolic disorders, type I or II absorptive hypercalciuria (HCU) or hyperuricosuria (HUCU) was detected in 29 patients; they received a specific drug therapy (thiazide or allopurinol) for a mean period of 45.7 months. Twenty patients without initial metabolic disorders were given general metaphylactic recommendations (high fluid intake, no excessive calcium, oxalate, protein and purine intake).