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Progress in Iron Research pp 157–164Cite as

Bacterioferritin: A Hemoprotein Member of the Ferritin Family

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 356))

Abstract

Ferritin has been known in eukaryotic cells for over 50 years1 but only in the last 15 years has a ferritin-like molecule been recognized in bacterial systems. In 1979 2 the hemoprotein originally designated3 as Azotobacter vinelandii cytochrome b557.5 was shown to be ferritin-like in character on the basis of subunit size and composition, electron microscopy of the holoprotein, and physical characterization of the core iron. 2 Since this initial identification of bacterioferritin its presence has been established in a wide variety of prokaryotic organisms including Escherichia coli, 4 Pseudomonas aeruginosa 5 Nitrobacter winogradskii 5 Mycobacterium paratuberculosis, 7 Synechocystis P.C.C. 6803, 8 Yersinia pestis 9 and Rhodobacter capsulatus. 10 In each of the above species heme in the form of extractable protoporphyrin IX is intimately associated with the protein.

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Author information

Authors and Affiliations

  1. Clinton Township, Exxon Research and Engineering Co., Route 22 E, Annandale, New Jersey, 08801, USA

    Edward I. Stiefel, Matthew J. Grossman, Stephen M. Hinton, Vera Minak-Bernero, Roger C. Prince & Richard E. Bare

  2. Stanford Synchrotron Radiation Laboratory, P.O Box 4349, Bin 69, Stanford, California, 94309, USA

    Graham N. George

  3. Department of Chemistry and Biochemistry, Brigham Young University, Provo, Utah, 84602, USA

    Gerald D. Watt

Authors
  1. Edward I. Stiefel
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  2. Matthew J. Grossman
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  3. Stephen M. Hinton
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  4. Vera Minak-Bernero
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  5. Roger C. Prince
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  6. Richard E. Bare
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  7. Graham N. George
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  8. Gerald D. Watt
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Editors and Affiliations

  1. Shaare Zedek Medical Center and Hebrew University of Jerusalem, Jerusalem, Israel

    Chaim Hershko

  2. The Hebrew University Hadassah Medical School, Jerusalem, Israel

    Abraham M. Konijn

  3. Albert Einstein College of Medicine, Bronx, New York, USA

    Philip Aisen

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© 1994 Springer Science+Business Media New York

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Stiefel, E.I. et al. (1994). Bacterioferritin: A Hemoprotein Member of the Ferritin Family. In: Hershko, C., Konijn, A.M., Aisen, P. (eds) Progress in Iron Research. Advances in Experimental Medicine and Biology, vol 356. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2554-7_18

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  • DOI: https://doi.org/10.1007/978-1-4615-2554-7_18

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6090-2

  • Online ISBN: 978-1-4615-2554-7

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