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From Voltammetry to Industrial Plant: Electrochemical Synthesis of DL-Homocysteine from DL-Homocystine — An Example of Scale-Up

  • Gaspar Sánchez-Cano
  • Vicente Montiel
  • Vicente García
  • Antonio Aldaz
  • Eduardo Elías

Abstract

An industrial process for the electrochemical synthesis of DL-Homocysteine from DL-Homocystine is described. DL-Homocysteine is a key intermediate for the synthesis of Citiolone (a powerful agent used to treat bronchitis and nasal catarrh). The work starts with a fundamental study, the voltammetric behaviour of DL-Homocystine, followed by a laboratory and pilot plant study and finishes with the development of an industrial process (30 tons/year of DL-Homocistine electroreduced). The method avoids the use of hazardous and polluting reductants such as Zn/H+. The figures of merit are a material yield of 95%, production over 200kg/m2day and a energy cost less than 2 kWh/kg.

Keywords

Hydrogen Evolution Current Efficiency Electrochemical Reduction Electrochemical Synthesis Cathodic Reduction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • Gaspar Sánchez-Cano
    • 1
  • Vicente Montiel
    • 1
  • Vicente García
    • 1
  • Antonio Aldaz
    • 1
  • Eduardo Elías
    • 2
  1. 1.Departamento de Química FísicaUniversidad de AlicanteAlicanteSpain
  2. 2.Prodesfarma SA (D.M.P.)Sant CeloniSpain

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