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Issues and Reviews in Teratology pp 37–55Cite as

In Utero Exposure to Carbamazepine Effects on the Fetus

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Abstract

Carbamazepine (CBZ) is an iminostilbene with a tricyclic structure. It has been in clinical use for more then twenty years and has often been considered the anticonvulsant of choice for women with seizure disorders who wish to have a pregnancy. This was based on small series of exposed women. Recently, Morrison and Rieder (1993) made a survey of the usual practice among Canadian neurologists with respect to the management of epilepsy during pregnancy. In a majority (75%) CBZ was mentioned as the drug of choice. Epidemiological studies published during the past five years indicate an increased risk for some adverse reproductive outcome, however.

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Authors and Affiliations

  1. Institut Européen des Génomutations, 86 Rue Edmond Locard, F-69005, Lyon, France

    Elisabeth Robert

  2. Tornblad Institute, University of Lund, Biskopsgatan 7, S-224 65, Lund, Sweden

    Bengt Källén

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  1. Elisabeth Robert
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  2. Bengt Källén
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Editors and Affiliations

  1. Children’s Hospital Research Foundation and Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA

    Harold Kalter

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Robert, E., Källén, B. (1994). In Utero Exposure to Carbamazepine Effects on the Fetus. In: Kalter, H. (eds) Issues and Reviews in Teratology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2512-7_2

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  • DOI: https://doi.org/10.1007/978-1-4615-2512-7_2

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