Antibody-Forming Cells (AFCs) in the Lung Lymphoid Tissue After Primary and Secondary Immunization Through Different Routes:A Semiquantitative Analysis in Adult Rats Using T Dependent (TNP-KLH) and T-Independent Antigens (TNP-LPS)
Part of the
Advances in Experimental Medicine and Biology
book series (AEMB, volume 355)
Despite pioneer reports emphasizing the mutual resemblances of the bronchus-associated lymphoid tissue (BALT) and the gut-associated lymphoid tissue (GALT), so claiming the relationship of BALT to the so-called mucosa-associated lymphoid tissue (MALT), the evidence is merely circumstantial. To date, there are important differences in the histological organization of both tissues1,2. The lymphoepithelium condition of the epithelium covering the lung lyraphoid aggregates can only be observed in locally immunized animals and even in that situation the existence of M-like cells in the epithelium is controversial2,3. Moreover, germinal centers have only been reported in the BALT after extensive immunization2.
KeywordsMigration Glycerine Acetone Respiration Germinal
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