Abstract
Peyer’s patches (PP), together with mesenteric lymph nodes (MLN) and tonsils, belong to the MALT (Mucosa Associated Lymphoid Tissue). Here, plasma cell precursors are generated that will produce protective slgA antibodies after maturation in the epithelia of the respiratory, alimentary and genito-urinary tracts. PP are known to generate plasma and memory cells of the IgA isotype upon stimulation by gut-derived antigens, while MLN are more involved in the generation of plasma cells of the IgG or IgE isotype upon stimulation with villi-derived antigens.
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van Halteren, A.G.S., Mebius, R.E., Kraal, G. (1994). Vascular Addressin Expression in Peyer’S Patches: an in Vivo Study of Site-Associated Regulation. In: Heinen, E., Defresne, M.P., Boniver, J., Geenen, V. (eds) In Vivo Immunology. Advances in Experimental Medicine and Biology, vol 355. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2492-2_21
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DOI: https://doi.org/10.1007/978-1-4615-2492-2_21
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