Abstract
A very new proto-oncogene, called c-cbl, has recently been described. This oncogene was discovered as a virally transduced oncogene responsible for inducing pre B cell lymphoma in mice (Holmes et al., 1986; Langdon et al., 1989a).
Keywords
- Scanning Densitometry
- Human Thymocyte
- Leucine Zipper Family
- Relative Hybridization Intensity
- Defective Cell Cycle
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References
Auwerx, J.H., Deeb, S., Brunzell, J.D., Peng, R. and Chait A., 1988, Transcriptional activation of the lipoprotein lipase E genes accompanies differentiation in some human macrophage-like cell lines, Biochemistry 27:2651.
Blake, T.J., Shapiro, M., Morse III, H.C. and Langdon W.Y., 1991, The sequences of the human and mouse c-cbl proton-oncogenes show v-cbl was generated by a large truncation encompassing a proline-rich domain and a leucine zipper-like motif, Oncogene. 6:653.
Colombel, M., Olsson, C.A., Ng P-Y and Buttyan, R., 1992, Hormone-regulated apoptosis results from reentry of differentiated prostate cells into a defective cell cycle, Cancer Res. 52:4313.
Holmes, K.L., Langdon, W.Y., Fredrickson, T.N., Coffman, R.L., Hoffman, P.M., Hartley, J.W. and Morse III, H.C., 1986, Analysis of neoplasms induced by Cas-Br-M tumor extracts, J. Immunol. 137:679.
Langdon, W.Y., Hartley, J.W., Klinken, S.P., Ruscetti, S.K. and Morse III, H.C., 1989a, V-cbl, an oncogene from a dual recombinant murine retrovirus that induces early B-lineage lymphomas, Proc. Natl. Acad. Sci. USA 86:1168.
Langdon, W.Y., Heath, K.G. and Blake, T.J., 1992, The localization of the products of the c-cbl and v-cbl oncogenes during mitosis and transformation, Current topics in Microbiol. and Immunol. 182:467.
Langdon W.Y., Hyland, C.D., Grumont, R.J. and Morse III, H.C., 1989b, The c-cbl proton-oncogene is preferentially expressed in thymus and testis tissue and encodes a nuclear protein, J. Virol. 63:5420.
Lohka, M.J., Hayes, M.K. and Maller J.L., 1988, Purification of maturation-promoting factor, an intracellular regulator of early mitotic events, Proc. Natl. Acad. Sci. USA 85:3009.
Makover, D., Cuddy, M., Yum, S., Bradley, K., Alpers, J., Sukhatme, V. and Reed, J. C, 1991, Phorbol ester-mediated inhibition of growth and regulation of proto-oncogene expression in the human T cell leukemia line Jurkat, Oncogene, 6:455.
Regnier, D., Kozak, CA., Kingsley, D.M., Jenkins, N.A., Copeland, N.G., Langdon, W.Y. and Morse III, H.C., 1989, Identification of two murine loci homologous to the v-cbl oncogene, J. Virol. 63:3678.
Rovera, G., Olashaw, N. and Meo, P., 1980, Terminal differentiation in human promyelocytic leukaemic cells in the absence of DNA synthesis, Nature. 284:69.
Savage, P.D., Shapiro, M., Langdon, W.Y., Geurts van Kessel, A.D., Seuanez, H.N., Akao, Y., Croce, C, Morse III, H.C and Kersey, J.H., 1991, Relationship of the human protooncogene CBL2 on 11q23 to the t(4;ll), t(ll;22), and t(11;14) breakpoints, Cytogenet Cell Genet. 56:112.
Warner, A., 1985, The role of gap junctions in amphibian development, 1985, J. Embryol. Exp. Morphol., Suppl. 81:365.
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© 1994 Springer Science+Business Media New York
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Thaon, S., Quaranta, JF., Régnier, D. (1994). Genetic Expression of the C-Cbl Proto-Oncogene in Human Thymocytes. In: Heinen, E., Defresne, M.P., Boniver, J., Geenen, V. (eds) In Vivo Immunology. Advances in Experimental Medicine and Biology, vol 355. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2492-2_2
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DOI: https://doi.org/10.1007/978-1-4615-2492-2_2
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