Interferon and Copolymer I Treatment in Multiple Sclerosis: Clinical and Pathobiological Implications

  • Kenneth P. Johnson
  • Hillel S. Panitch
Part of the NATO ASI Series book series (NSSA, volume 258)


Multiple sclerosis (MS), although well-described clinically and pathologically for over 120 years, is only now poised for a new era of improved therapy brought about primarily by findings obtained from clinical research. Over the past 12 years, various investigations of new treatments have not only identified effective agents but have provided unexpected new insights into the basic mechanisms of disease activity in MS. The combination of carefully designed and conducted clinical trials, coupled with serial MRI studies of the brain, has allowed us to determine the therapeutic benefit of one and perhaps two treatments with low risk and toxicity which are likely to be available to the general MS community within 6 to 24 months.


Multiple Sclerosis Myelin Basic Protein Experimental Allergic Encephalomyelitis Beta Interferon Tamic Acid 
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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Kenneth P. Johnson
    • 1
  • Hillel S. Panitch
    • 1
  1. 1.Department of NeurologyUniversity of Maryland at BaltimoreBaltimoreUSA

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