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Comparisons of Tear Proteins in the Cow, Horse, Dog and Rabbit

  • Harriet J. Davidson
  • Gary L. Blanchard
  • Paul C. Montgomery
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 350)

Abstract

Tear proteins play a major role in normal corneal health.1 Several changes in tear proteins have been shown to be related to direct corneal irritation.2 In veterinary medicine, differences between species often occurs in the clinical response to corneal irritation and external ocular disease. These differences may be a reflection of various factors including tear proteins. There is little information available on tear film properties in veterinary species. Some studies have evaluated the protein concentration for selected species; with little information on the molecular weight distribution of the proteins.3–7 This project was undertaken to determine normal protein concentration and molecular weight distribution of tear proteins in the cow, the horse, the rabbit and the dog.

Keywords

Molecular Weight Distribution Lacrimal Gland Quarter Horse Gland Fluid High Molecular Weight Range 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    R.A. Moses, W.M. Hart. “Adler’s Physiology of the Eye”. CV Mosby C., St Louis (1987).Google Scholar
  2. 2.
    T. Vinding, J.S. Eriksen, N.V. Vielsen. The concentration of lysozyme and secretory IgA in tears from healthy persons with and without contact lens use. Acta Ophth. 65:23 (1987).CrossRefGoogle Scholar
  3. 3.
    D.C. Maidment, D.E. Kidder, M.N. Taylor. Electrolyte and protein levels in bovine tears. Br. Vet. J. 141:169 (1985).PubMedCrossRefGoogle Scholar
  4. 4.
    R.E. Halliwell, N.T. Gorman. “Veterinary Clinical Immunology”. WB Saunders, Philadelphia (1989).Google Scholar
  5. 5.
    R. Barrera, A. Jimenez, R. Lopez, M.C. Mane, J.F. Rodriguez, J.M. Molleda. Evaluation of total protein content in tears of dogs by polyacrylamide gel disk electrophoresis. Am. J. Vet. Res. 53:454 (1992).PubMedGoogle Scholar
  6. 6.
    S.R. Robert, O.F. Erickson. Dog tear secretion and tear proteins. J. Sin. Animal Prac. 3:1 (1965).CrossRefGoogle Scholar
  7. 7.
    L. Thorig, E.J. van Agtmaal, E. Glasius, J.L. Tan, N.J. van Haeringen. Comparison of tears and lacrimal gland fluid in the rabbit and guinea pig. Curr. Eye Res. 4:913 (1985).PubMedCrossRefGoogle Scholar
  8. 8.
    A. Johnstone, R. Thorpe. “Immunochemistry in Practice,” Blackwell Scientific Publications, Boston (1988).Google Scholar
  9. 9.
    A. Kuizenga, N.J. van Haeringen, A. Kijlstra. SDS-minigel electrophoresis of human tears. Invest. Ophthalmol. Vis. Sci. 32:281 (1991).Google Scholar
  10. 10.
    H.E. Schaffer, R.R. Sederoff. Improved estimation of DNA fragment length from agarose gels. Anal. Chem. 115:113 (1981).Google Scholar
  11. 11.
    J.H. Prince. “Comparative Anatomy of the Eye”. Charles C Thomas, Springfield (1956).Google Scholar
  12. 12.
    P.T. Janssen, O.P. Van Biejsterveld. Comparison of electrophoretic techniques for the analysis of human tear fluid proteins. Clin. Chim. Acta 114:207 (1981).PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Harriet J. Davidson
    • 1
  • Gary L. Blanchard
    • 2
  • Paul C. Montgomery
    • 3
  1. 1.College of Veterinary MedicineKansas State UniversityManhattanUSA
  2. 2.College of Veterinary MedicineMichigan State UniversityEast LansingUSA
  3. 3.Department of Immunology and MicrobiologyWayne State University Medical SchoolDetroitUSA

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