Sjögren’s Syndrome — Close to Cause and Cure?
Sjögren’s syndrome (SS) is a chronic autoimmune disease associated with the production of rheumatoid factor and other autoantibodies (1). Because it is characterized by lymphocytic and plasma cell infiltration and destruction of salivary and lacrimal glands, SS gives rise to the characteristic symptoms of dry mouth and dry eyes. The term “autoimmune exocrinopathy” has been applied to this disease. The lymphocytic infiltration can extend to other, more-vital organs, so SS is both a systemic (like SLE) and a localized (like autoimmune thyroiditis) autoimmune disorder.
KeywordsSystemic Lupus Erythematosus Chronic Fatigue Syndrome Acquire Immune Deficiency Syndrome Lacrimal Gland Monoclonal Immunoglobulin
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