Borrelia Burgdorferi Infection in Mice: Aspects of Inflammation and Immune Responses

  • Naveed Honarvar
  • Elena Böggemeyer
  • Chris Galanos
  • Manuel Modolell
  • Dietmar Vestweber
  • Reinhard Wallich
  • Michael D. Kramer
  • Ulrich E. Schaible
  • Markus M. Simon
Part of the NATO ASI Series book series (NSSA, volume 260)


Lyme disease is caused by the spirochete Borrelia burgdorferi (B.burgdorferi) and to date the most common vector borne infectious disease of the temperate climate 1. The multifacetal nature of the illness which affects skin, joints, nervous system and heart as well as the inability of many patients to control infection, in spite of their specific immune responses, has been a considerable challenge for clinicians and scientists1. Two aspects of B.burgdorferi infections, i.e., the pathogenesis of Lyme disease with its chronic course of tissue destruction and the role of the immune response in protection, have attracted attention in the past.


Lyme Disease Cold Spring Harbor Laboratory Borrelia Burgdorferi Severe Combine Immunodeficiency Peripheral Blood Lympho 
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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Naveed Honarvar
    • 1
  • Elena Böggemeyer
    • 1
  • Chris Galanos
    • 1
  • Manuel Modolell
    • 1
  • Dietmar Vestweber
    • 2
  • Reinhard Wallich
    • 3
  • Michael D. Kramer
    • 4
  • Ulrich E. Schaible
    • 1
  • Markus M. Simon
    • 1
  1. 1.Max-Planck-Institut für Immunbiologie FreiburgGermany
  2. 2.Hans-Spemann-Labor der Max-Planck-GesellschaftFreiburgGermany
  3. 3.Abteilung Angewandte ImmunologieDeutsches KrebsforschungszentrumHeidelbergGermany
  4. 4.Institut für Immunologie und Serologie der Universität HeidelbergHeidelbergGermany

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