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High-Dose Chemotherapy and Autologous Stem Cell Transplantation for Breast Cancer

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Book cover Technical and Biological Components of Marrow Transplantation

Part of the book series: Cancer Treatment and Research ((CTAR,volume 76))

Abstract

Carcinoma of the breast ends the life of nearly 50,000 women each year in the United States [1]. Refinements in surgery and radiation have improved cosmesis and local control but have failed to deal with the insidious systemic nature of this disease. Conventional dose adjuvant chemotherapy has also failed to impact national mortality figures [2]. At historically applied doses, adjuvant chemotherapy represents inadequate systemic therapy for a large proportion of patients.

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Weaver, C.H., Birch, R., Schwartzberg, L.S., West, W.H. (1995). High-Dose Chemotherapy and Autologous Stem Cell Transplantation for Breast Cancer. In: Buckner, C.D., Clift, R.A. (eds) Technical and Biological Components of Marrow Transplantation. Cancer Treatment and Research, vol 76. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2013-9_3

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