Adenosine 5’-Triphosphate Receptor — Mediated Currents in Rat Intracardiac Neurons

  • T. J. Nutter
  • D. J. Adams

Abstract

Adenosine 5’-triphosphate (ATP) activates a nonselective cation conductance in a variety of cultured peripheral neurons, including rat and bullfrog sensory neurons [1,2], rat sympathetic neurons [3], rat and guinea-pig parasympathetic neurons [4,5], and guinea-pig celiac neurons [6–9]. ATP-mediated responses have been described also in central neurons [10–12]. ATP has recently been shown to act as a fast excitatory transmitter at neuro-neuronal synapses in rat cultured celiac neurons [6,8] and in rat medial habenula slice preparations [13]. Thus, ATP has become increasingly recognized as a neurotransmitter that is active in both the central and peripheral nervous systems.

Keywords

Permeability Attenuation Adenosine Penicillin Streptomycin 

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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • T. J. Nutter
  • D. J. Adams

There are no affiliations available

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