Dose-Dependent Effects of Oxytocin on the Microcirculation in the Mammary Gland of the Lactating Rat

  • Stephen R. Davis
  • Vicki C. Farr
  • Colin G. Prosser

Abstract

A number of studies have described the microcirculation of the rodent mammary gland usually through histological or vascular corrosion casting methodology (e.g. Yasugi et al., 1989). The objective of the study described below was to develop a method for in vivo microscopy of the mammary gland of the lactating rat and to observe the behaviour of the microcirculation during milk ejection following injection of oxytocin.

References

  1. Bissett, G.W., Clark, B.J., Haldar, J., Harris, M.C., Lewis, G.P., Rocha e Silva, M., 1967, The assay of milk ejecting activity in the lactating rat, Br. J. Pharmac. Chemother. 31:537.Google Scholar
  2. Cross, B.A. and Silver, I.A., 1962, Mammary oxygen tension and the milk ejection mechanism, J. Endocrinology 23:375.CrossRefGoogle Scholar
  3. Yasugi, T., Kaido, T. and Uehara, Y., 1989, Changes in density and architecture of microvessels of the mammary gland during pregnancy and lactation, Arch. Histol. Cytol. 52:115.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • Stephen R. Davis
    • 1
  • Vicki C. Farr
    • 1
  • Colin G. Prosser
    • 1
  1. 1.Ruakura Agricultural Research CentreDairying Research CorporationHamiltonNew Zealand

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