Mouse Class 3 Aldehyde Dehydrogenases
The Class 3 aldehyde dehydrogenases include the 2,3,7,8-tetrachlorodibenzo-p-dioxin (dioxin, TCDD)-inducible cytosolic form (ALDH3c) and the constitutive microsomal form (ALDH3m), which is also TCDD-inducible. Table 1 summarizes the ALDH nomenclature used in this chapter. It might be noted that the Committee on Standardized Genetic Nomenclature for Mice is adamant about keeping the mouse gene designations the same as they have been for several decades.
KeywordsAldehyde Dehydrogenase ALDH Gene Nontranslated Region Mouse Class Aldehyde Dehydrogenase Gene
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- Asman, D.C., Takimoto, K., Pitot, H.C., and Lindahl, R., 1993, Organization of the rat class 3 aldehyde dehydrogenase gene, J. Biol. Chem. 268: 12530.Google Scholar
- Dunn, T.J., Koleske, J.E., Lindahl, R., and Pitot, H.C., 1989, Phenobarbital-inducible aldehyde dehydrogenase in the rat: cDNA sequence and regulation of the mRNA by phenobarbital in responsive rats, J. Biol. Chem. 264: 13507.Google Scholar
- Green, E.L., 1981, Genetics and probability in animal breeding experiments. New York: MacMillan Publishing Company, Inc.Google Scholar
- Hsu, L.C., Chang, W-C., Shibuya, A., and Yoshida, A., 1992, Human stomach aldehyde dehydrogenase cDNA and genomic cloning, primary structure, and expression in Escherichia coli, J. Biol. Chem. 267: 3030.Google Scholar
- Nebert, D.W., Kozak, CA., Lindahl, R., and Vasiliou, V., 1994, Mouse microsomal Class 3 aldehyde dehydrogenase: AHD3 cDNA sequence, chromosomal mapping, and dioxin inducibility, The Toxicologist 14: 409.Google Scholar
- Nebert, D.W. and Vasiliou, V., 1993, Involvement of the electrophile-responsive element (EpRE) in the murine chromosome 7-mediated derepression of the Phase II [Ah] battery genes, The Toxicologist 13: 134.Google Scholar
- Vasiliou, V., Reuter, S.F., and Nebert, D.W., 1994, Organization and characterization of the murine cytosolic TCDD-inducible aldehyde dehydrogenase (Ahd4) gene, The Toxicologist 14: 410.Google Scholar