Expression of Adhesion Molecules on the Surface of Malignant Cells and Cell Lines
Cell-cell adhesion molecules (CAMs) have been implicated not only in intercellular recognition (adhesion of various types of leukocytes to other cells and to a component of extracellular matrix), but also in morphogenetic events, regeneration, tumor invasion and metastasis. Some CAMs may primarily establish stable bonds between cells, whereas others may be expected to be involved in signalling between cells. Based on nucleic acid sequence data, the majority of known CAMs can be grouped into the following families: the integrin superfamily (VLA antigens, leukocyte integrins, cytoadhesins); the immunoglobulin superfamily; the selectin family and the cadherin family.1–5
KeywordsLymphoma Leukemia Integrin Meijer Metrizoate
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