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A Basement Membrane Molecule Preferentially Associated with Mucosal Post-Capillary Venules

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Advances in Mucosal Immunology

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 371))

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Abstract

B cell lymphomas of mucosa associated lymphoid tissue (MALT-type lymphomas) are a distinct group of tumours which arise in extranodal sites including the stomach, salivary gland, thyroid and lung.1 The onset of lymphomas in the salivary gland and thyroid is known to be preceeded by autoimmune disease, though it is not clear whether the tumour cells themselves in such lymphomas recognise autoantigens.2,3 We have recently shown that low grade MALT-type lymphomas of the gastrointestinal tract recognise autoantigens.4 In this study we have investigated an autoantigen recognised by one such case of low grade B cell gastric lymphoma which we believe may itself have a significant role in mucosal immunity.

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References

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© 1995 Springer Science+Business Media New York

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Hussell, T., Isaacson, P.G., Spencer, J. (1995). A Basement Membrane Molecule Preferentially Associated with Mucosal Post-Capillary Venules. In: Mestecky, J., Russell, M.W., Jackson, S., Michalek, S.M., Tlaskalová-Hogenová, H., Šterzl, J. (eds) Advances in Mucosal Immunology. Advances in Experimental Medicine and Biology, vol 371. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1941-6_20

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  • DOI: https://doi.org/10.1007/978-1-4615-1941-6_20

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5796-4

  • Online ISBN: 978-1-4615-1941-6

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