Stimulation of Galt by Nocardia Delipidated Cell Mitogen (NDCM) in Irradiated Germfree Piglets
Ionizing radiation seriously damages gastrointestinal compartments of the mucosal immune system. Even small doses lead to mitotic disturbances, death of stem cells in crypts of Lieberkuhn, injury of the epithelium and endothelium and extensive edema and hemorrhages. Low doses of ionizing radiation affect mostly lymphocytes which are extremely radiosensitive cells. Their morphology is influenced by doses as low as 0.25 Gy after 2 h. Lymphocytes which are in the interphase of cell cycle are killed after irradiaton by interphase death, a kind of programmed cell death.
KeywordsEthyl Acetone Chloroform Interferon Trehalose
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