Skip to main content

Effective Synaptic Currents Generated in Cat Spinal Motoneurones by Activating Descending and Peripheral Afferent Fibres

  • Chapter
Alpha and Gamma Motor Systems

Abstract

Understanding how synaptic inputs from segmental and descending systems shape motor output from the spinal cord requires detailed descriptions of the relative magnitudes of the synaptic currents produced by the different systems and their pattern of distribution within a motoneurone pool (Burke, 1981; Heckman & Binder, 1990). Knowledge of how distinct synaptic inputs interact when they are activated concurrently and quantitative expressions for how synaptic currents are transduced into spike trains by motoneurones are equally important.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Brillinger, D. R., Bryant, H. L. & Segundo, J. P. (1976) Identification of synaptic interactions. Biol. Cybern. 22, 213–228.

    Article  PubMed  CAS  Google Scholar 

  • Burke, R. E. (1981) Motor units: anatomy, physiology, and functional organization. In Handbook of Physiology, The Nervous System, Motor Control ed. Brooks, V. B. pp 345–422. American Physiological Society. Bethesda.

    Google Scholar 

  • Burke, R. E., Jankowska, E. & Ten Bruggencate, G. (1970) A comparison of peripheral and rubrospinal input to slow and fast twitch motor units of triceps surae. J. Physiol. 207, 709–732.

    PubMed  CAS  Google Scholar 

  • Burke, R. E., Rymer, W. Z. & Walsh, J. V. (1976) Relative strength of synaptic input from short-latency pathways to motor units of defined type in cat medial gastrocnemius. J. Neurophvsiol. 39, 447–458.

    CAS  Google Scholar 

  • Cope, T. C., Fetz, E. E. & Matsumura, M. (1987) Cross-correlation assessment of synaptic strength of single Ia fibre connections with triceps surae motoneurones in cats. J. Physiol. 390, 161–188.

    PubMed  CAS  Google Scholar 

  • Fetz, E. E., Cheney, P. D., Mewes, K. & Palmer, S. (1989) Control of forelimb muscle activity by populations of corticomotoneuronal and rubromotoneuronal cells. Prog. Brain Res. 80, 437–449.

    Article  PubMed  CAS  Google Scholar 

  • Finkel, A. S. & Redman, S. J. (1983) The synaptic current evoked in cat spinal motoneurones by impulses in single group Ia axons. J. Physiol. 342, 615–32.

    PubMed  CAS  Google Scholar 

  • Friedman, W. A., Sypert, G. W., Munson, J. B. & Fleshman, J. W. (1981) Recurrent inhibition in type-identified motoneurons. J. Neurophysiol. 46, 1349–1359.

    PubMed  CAS  Google Scholar 

  • Granit, R. & Renkin, B. (1961) Net depolarization and discharge rate of motoneurones, as measured by recurrent inhibition. J. Physiol. 158, 461–475.

    PubMed  CAS  Google Scholar 

  • Grillner, S., Hongo, T. & Lund, S. (1970) The vestibulospinal tract. Effects on alpha-motoneurones in the lumbosacral spinal cord in the cat. Exp. Brain Res. 10, 94–120.

    Article  PubMed  CAS  Google Scholar 

  • Heckman, C. J. & Binder, M. D. (1988) Analysis of effective synaptic currents generated by homonymous Ia afferent fibers in motoneurons of the cat. J. Neurophysiol. 60, 1946–1966.

    PubMed  CAS  Google Scholar 

  • Heckman, C. J. & Binder, M. D. (1990) Neural mechanisms underlying the orderly recruitment of motoneurons. In The Segmental Motor System, eds. Binder, M. D. & Mendell, L. M. pp 182–204. Oxford University Press. New York.

    Google Scholar 

  • Heckman, C. J. & Binder, M. D. (1991) Analysis of la-inhibitory synaptic input to cat spinal motoneurons evoked by vibration of antagonist muscles. J. Neurophysiol. 66, 1888–1893.

    PubMed  CAS  Google Scholar 

  • Heckman, C. J. & Binder, M. D. (1993) Computer simulations of motoneuron firing rate modulation. J. Neurophysiol. 69, 1005–1008.

    PubMed  CAS  Google Scholar 

  • Hultborn, H., Katz, R. & Mackel, R. (1988) Distribution of recurrent inhibition within a motor nucleus. II. Amount of recurrent inhibition in motoneurons to fast and slow units. Acta Physiol. Scand. 134, 363–374.

    Article  PubMed  CAS  Google Scholar 

  • Hultborn, H., Lindstrom, S. & Wigstorm, H. (1979) On the function of recurrent inhibition in the spinal cord. Exp. Brain Res. 37, 399–403.

    Article  PubMed  CAS  Google Scholar 

  • Kernell, D. (1966) The repetitive discharge of motoneurones. In Muscular Afferents and Motor Control. Nobel Symp. I. ed. Granit, R. pp 351–362. Almqvist and Wiksell, Stockholm.

    Google Scholar 

  • Kernell, D. (1979) Rhythmic properties of motoneurones innervating muscle fibres of different speed in m. gastrocnemius medialis of the cat. Brain Res. 160, 159–162.

    Article  PubMed  CAS  Google Scholar 

  • Kernell, D. (1983) Functional properties of spinal motoneurons and gradation of muscle force. Adv. Neurol. 39, 213–226.

    PubMed  CAS  Google Scholar 

  • Lindsay, A. D. & Binder, M. D. (1991) Distribution of effective synaptic currents underlying recurrent inhibition in cat triceps surae motoneurons. J. Neurophysiol. 65, 168–177.

    PubMed  CAS  Google Scholar 

  • Munson, J. B. (1990) Synaptic inputs to type-identified motor units. In The Segmental Motor System. eds. Binder, M. D. & Mendell, L. M. pp 291–307. Oxford University Press, New York.

    Google Scholar 

  • Powers, R. K., Robinson, F. R., Konodi, M. A. & Binder, M. D. (1992) Effective synaptic current can be estimated from measurements of neuronal discharge. J. Neurophysiol. 68, 964–968.

    PubMed  CAS  Google Scholar 

  • Powers, R. K., Robinson, F. R., Konodi, M. A. & Binder, M. D. (1993) Distribution of rubrospinal synaptic input to cat triceps surae motoneurons. J. Neurophysiol. 70, 1460–1468.

    PubMed  CAS  Google Scholar 

  • Rall, W., Burke, R. E., Smith, T. G., Nelson, P. G. & Frank, K. (1967) Dendritic location of synapses and possible mechanisms for the monosynaptic EPSP in motoneurons. J. Neurophysiol. 30, 1169–1193.

    PubMed  CAS  Google Scholar 

  • Redman, S. (1976) A quantitative approach to the integrative function of dendrites. In International Review of Physiology: Neurophysiology. ed. Porter, R. pp. 1–36. University Park Press, Baltimore.

    Google Scholar 

  • Schwindt, P. C. & Calvin, W. H. (1973a) Equivalence of synaptic and injected current in determining the membrane potential trajectory during motoneuron rhythmic firing. Brain Res. 59, 389–394.

    Article  PubMed  CAS  Google Scholar 

  • Schwindt, P. C. & Calvin, W. H. (1973b) Nature of conductances underlying rhythmic firing in cat spinal motoneurons. J. Neurophysiol. 36, 955–973.

    PubMed  CAS  Google Scholar 

  • Segev, I., Fleshman, J. W. J. & Burke, R. E. (1990) Computer simulation of group Ia EPSPs using morphologically realistic models of cat alpha-motoneurons. J. Neurophysiol. 64, 648–660.

    PubMed  CAS  Google Scholar 

  • Shapovalov, A. I. (1972) Extrapyramidal monosynaptic and disynaptic control of mammalian alpha-motoneurons. Brain Res. 40, 105–115.

    Article  PubMed  CAS  Google Scholar 

  • Stein, R. B. & Bertoldi, R. (1981) The Size Principle: A Synthesis of Neurophysiological Data. Karger, Basel.

    Google Scholar 

  • Stuart, G. J. & Redman, S. J. (1990) Voltage dependence of Ia reciprocal inhibitory currents in cat spinal motoneurones. J. Physiol. 420, 111–125.

    PubMed  CAS  Google Scholar 

  • Westcott, S. L., Powers, R. K., Robinson, F. R., Konodi, M. A. & Binder, M. D. (1993) Comparison of vestibulospinal synaptic input and Ia afferent synaptic input in cat triceps surae motoneurons. The Physiologist 36, A20.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1995 Springer Science+Business Media New York

About this chapter

Cite this chapter

Binder, M.D., Powers, R.K. (1995). Effective Synaptic Currents Generated in Cat Spinal Motoneurones by Activating Descending and Peripheral Afferent Fibres. In: Taylor, A., Gladden, M.H., Durbaba, R. (eds) Alpha and Gamma Motor Systems. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1935-5_3

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-1935-5_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5793-3

  • Online ISBN: 978-1-4615-1935-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics