Depression of Recurrent Inhibition of the Soleus and Wrist Flexor Motor Nuclei by Magnetic Brain Stimulation in Humans

  • R. Mazzocchio
  • J. C. Rothwell
  • A. Rossi


Recurrent inhibition of alpha-motoneurones via motor axon collaterals and Renshaw cells is regarded as a prominent organisational feature of the motor nuclei to the limb muscles. In the cat, various supraspinal structures can influence the activity of Renshaw cells, including the pyramidal tract the activation of which depresses recurrent inhibition (see Baldissera, Hultborn & Illert, 1981). The question is whether such cortico-spinal depression of Renshaw cells is also present in humans and whether it represents a general strategy of cortical commands.


Motor Nucleus Cortical Stimulation Flexor Carpus Radialis Recurrent Inhibition Human Motor Cortex 
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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • R. Mazzocchio
    • 1
  • J. C. Rothwell
    • 2
  • A. Rossi
    • 1
  1. 1.Unita di Neurofisiologia dell’Istituto di Scienze Neurologichedell’Universita di SienaSienaItaly
  2. 2.MRC Human Movement and Balance UnitThe Institute of NeurologyLondonUK

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