Advertisement

Depression of Recurrent Inhibition of the Soleus and Wrist Flexor Motor Nuclei by Magnetic Brain Stimulation in Humans

  • R. Mazzocchio
  • J. C. Rothwell
  • A. Rossi

Abstract

Recurrent inhibition of alpha-motoneurones via motor axon collaterals and Renshaw cells is regarded as a prominent organisational feature of the motor nuclei to the limb muscles. In the cat, various supraspinal structures can influence the activity of Renshaw cells, including the pyramidal tract the activation of which depresses recurrent inhibition (see Baldissera, Hultborn & Illert, 1981). The question is whether such cortico-spinal depression of Renshaw cells is also present in humans and whether it represents a general strategy of cortical commands.

Keywords

Motor Nucleus Cortical Stimulation Flexor Carpus Radialis Recurrent Inhibition Human Motor Cortex 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. Baldissera, F., Hultborn, H. & Illert, M. (1981) Integration in spinal neuronal systems. In Handbook of Physiology, Section 1, The Nervous System, Volume 2, Motor Control, ed. Brooks, V.B. pp. 509–595. American Physiological Society, Bethesda.Google Scholar
  2. Katz, R., Mazzocchio, R., Penicaud, A. & Rossi, A. (1993) Distribution of homonymous and heteronymous recurrent inhibition in the human upper limb. Acta physiol. scand. 149, 183–198.PubMedCrossRefGoogle Scholar
  3. Mazzocchio, R., Rothwell, J. C., Day, B. L. & Thompson, P. D. (1994) Effect of tonic voluntary activity on the excitability of human motor cortex. J. Physiol. 474, 261–267.PubMedGoogle Scholar
  4. Rossi, A., Decchi, B. & Vecchione, V. (1992) Supraspinal influences on recurrent inhibition in humans. Paralysis of descending control of Renshaw cells in patients with mental retardation. EEG & Clin. Neurophysiol. 85, 419–424.CrossRefGoogle Scholar
  5. Rossi, A. & Mazzocchio, R. (1992) Renshaw recurrent inhibition to motoneurones innervating proximal and distal muscles of the human upper and lower limbs. In Muscle Afferents and Spinal Control of Movement. eds. Jami, L., Pierrot-Deseilligny, E. & Zytnicki, D. pp. 313–319, Pergamon Press, Oxford.Google Scholar

Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • R. Mazzocchio
    • 1
  • J. C. Rothwell
    • 2
  • A. Rossi
    • 1
  1. 1.Unita di Neurofisiologia dell’Istituto di Scienze Neurologichedell’Universita di SienaSienaItaly
  2. 2.MRC Human Movement and Balance UnitThe Institute of NeurologyLondonUK

Personalised recommendations