Skip to main content

Regulation of Normal Hemopoiesis

  • Chapter
Normal and Malignant Hematopoiesis

Part of the book series: Pezcoller Foundation Symposia ((PFSO,volume 6))

Abstract

The following is a summary of an oral presentation delivered because of the unavoidable absence of Dr. Ogawa from the meeting. No detailed referencing will be included as the subject has been reviewed extensively elsewhere (1,2,3).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Metcalf D, Nicola NA: The Colony Stimulating Factors: Molecular Biology to Clinical Aspects. Cam-bridge University Press, NY 1994 (in press).

    Google Scholar 

  2. Metcalf D: The colony-stimulating factors: discovery to clinical use. Phil Trans R Soc Lond B 333: 147–173, 1991.

    Article  CAS  Google Scholar 

  3. Metcalf D: Hemopoietic regulators: Redundancy or subtlety? Blood 82: 3515–3523, 1993.

    PubMed  CAS  Google Scholar 

  4. Li CL, Johnson GR: Rhodamine 123 reveals heterogeneity with murine Lin-, Sca-1+ hemopoietic stem cells. J Exp Med 175: 1443–1447, 1992.

    Article  PubMed  CAS  Google Scholar 

  5. Metcalf D: Lineage commitment of hemopoietic progenitor cells in developing blast cell colonies: Influence of colony stimulating factors. Proc Natl Acad Sci USA 88: 11310–11314, 1991.

    Article  PubMed  CAS  Google Scholar 

  6. Metcalf D: The cellular basis for enhancement interactions between stem cell factor and the colony stimulating factors. Stem Cells 11: Suppl 2:1–11, 1993.

    Article  PubMed  CAS  Google Scholar 

  7. Fukunaga R, Ishizaka-Ikeda E, Nagata S: Growth and differentiation signals mediated by different regions in the cytoplasmic domain of granulocyte-stimulating factor receptor. Cell 74 1079–1087. 1993.

    Article  PubMed  CAS  Google Scholar 

  8. Sakamaki K, Miyajima I, Kitamura T, Miyajima A: Critical cytoplasmic domains of the common beta subunit of the human GM-CSF, IL-3 and IL-5 receptors for growth signal transduction and tyrosine phosphorylation. EMBO J 11: 3541–3549, 1993.

    Google Scholar 

  9. Lieschke GJ, Grail D, Hodgson G, Metcalf D, Stanley E, Cheers C, Fowler, KJ. Basu S, Zhan YF, Dunn AR: Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency and impaired neutrophil mobilization. Blood 1994 (in press).

    Google Scholar 

  10. Stanley E, Lieschke GJ, Grail D, Metcalf D, Hodgson G, Gall JAM, Maher DW, Cebon J, Sinickas V, Dunn AR: Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology. Proc Natl Acad Sci USA 91: 5592–5596, 1994.

    Article  PubMed  CAS  Google Scholar 

  11. Wiktor-Jedrzejczak W, Urbanowska E, Aukerman SK, Pollard JW, Stanley ER, Ralph P, Ansari AA, Sell KW, Szperl M. Correction by CSF-1 of defects in the osteopetrotic op/op mouse suggests local, developmental and humoral requirements for this growth factor. Exp Hematol 19: 1049–1054, 1991.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1995 Springer Science+Business Media New York

About this chapter

Cite this chapter

Metcalf, D. (1995). Regulation of Normal Hemopoiesis. In: Mihich, E., Metcalf, D. (eds) Normal and Malignant Hematopoiesis. Pezcoller Foundation Symposia, vol 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1927-0_1

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-1927-0_1

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5789-6

  • Online ISBN: 978-1-4615-1927-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics