Abstract
This study was designed to elucidate whether previously observed enhanced mRNAs were due to accelerated transcription, enhanced mRNA stability or both mechanisms. We employed the nuclear run-on technique on myocardial nuclei and found the transcriptional induction of several genes, especially nuclear protooncogenes, Ca2+ regulating and heat shock protein genes.
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Knöll, R., Zimmermann, R., Schaper, W. (1995). Altered Gene Transcription Following Brief Episodes of Coronary Occlusions. In: Sideman, S., Beyar, R. (eds) Molecular and Subcellular Cardiology. Advances in Experimental Medicine and Biology, vol 382. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1893-8_18
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DOI: https://doi.org/10.1007/978-1-4615-1893-8_18
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