Aesthesiometry-Azelastine Eye Drops Reduce Corneal Sensitivity in Rabbits, But Not in Dogs and Humans

  • Klaus Krauser
  • Edith Schneider
  • Robert Hermann
  • Wolfgang Jahn


The active principle of Azelastine Eye Drops is Azelastine.HCl. Azelastine is a phthalazinone derivative which was synthetized and developed by ASTA Medica AG as an antiasthmatic and antiallergic compound. It is marketed as tablets and/or nasal spray in several countries as U.K., France, Spain, Germany, Japan, and others. A NDA is submitted in the United States.


Ophthalmic Solution Anesthetic Effect Filament Length Albino Rabbit Vehicle Solution 
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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • Klaus Krauser
    • 1
  • Edith Schneider
    • 2
  • Robert Hermann
    • 2
  • Wolfgang Jahn
    • 1
  1. 1.Institute of ToxicologyASTA Medica AGHalle/WestfalenGermany
  2. 2.Clinical Pharmacology UnitASTA Medica AGFrankfurt am MainGermany

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