Abstract
Ocular bioavailability is generally accepted to be extremely low compared to bioavailability obtained from conventional oral doses. Indeed, whereas ocular bioavailability is of the order of 1–3% (Lee and Robinson, 1986) a similar oral bioavailability would probably not be commercially acceptable. There is, therefore, a great potential need for improvement of the ocular bioavailability of almost all ophthalmic agents that penetrate the eye for their pharmacological effect.
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Grove, J., Chastaing, G., Quint, MP., Rozier, A., Plazonnet, B. (1995). Evaluation of the Effect of the Vehicle on Ocular Distribution and Bioavailability of Betaxolol. In: Weisse, I., Hockwin, O., Green, K., Tripathi, R.C. (eds) Ocular Toxicology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1887-7_16
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DOI: https://doi.org/10.1007/978-1-4615-1887-7_16
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