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Signal Transduction in T Cells Through the Interleukin 2 Receptor

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Cell Signal Transduction, Second Messengers, and Protein Phosphorylation in Health and Disease

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Abstract

Interleukin 2 (IL-2) plays a central role in the immune responses regulating the proliferation and differentiation of T lymphocytes1,2. The interaction of IL-2 with specific high affinity receptors (IL-2R) expressed on T cells upon activation induces T cell proliferation. However, the molecular bases of IL-2 induced signal transduction mechanism are poorly understood.

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Authors and Affiliations

  1. Centro de Biología Molecular “Severo Ochoa” (CSIC-UAM), Universidad Autónoma de Madrid Cantoblanco, 28049, Madrid, Spain

    Eva Cano, M. Angeles Muñoz-Fernández & Manuel Fresno

Authors
  1. Eva Cano
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  2. M. Angeles Muñoz-Fernández
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  3. Manuel Fresno
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Editor information

Editors and Affiliations

  1. Royal Academy of Sciences of Spain, Madrid, Spain

    A. Martin Municio

  2. Complutense University of Madrid, Madrid, Spain

    M. Teresa Miras-Portugal

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© 1994 Springer Science+Business Media New York

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Cano, E., Muñoz-Fernández, M.A., Fresno, M. (1994). Signal Transduction in T Cells Through the Interleukin 2 Receptor. In: Municio, A.M., Miras-Portugal, M.T. (eds) Cell Signal Transduction, Second Messengers, and Protein Phosphorylation in Health and Disease. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1879-2_13

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  • DOI: https://doi.org/10.1007/978-1-4615-1879-2_13

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5765-0

  • Online ISBN: 978-1-4615-1879-2

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