Occupations of Fathers before Conception and the Risk of Testicular Cancer in their Sons
Testicular cancer is a disease which occurs largely among young adult, white males. The incidence rate in Ontario in 1988 was 4 per 100,000 men per year. Among men aged 15–29 the rate was 7 and among men aged 30–44 the rate was 8 per 100,000. Testicular cancer has attracted recent attention because the incidence has been increasing in high incidence populations in Europe, North America, and Australia, yet the etiology remains largely unknown. Nearly all of these cancers arise in the germ cells. Germ cell tumours of the testis can be subdivided into distinct histologic subgroups. About half of the tumours are seminomas while the other half are often grouped together as nonseminomas and includes teratomas and choriocarcinomas (a small proportion of tumours have mixed seminoma and nonseminoma histology). These two groups have distinct age distributions with nonseminomas occurring more commonly at younger ages than seminomas which peak during the 30’s. This suggests that they may have different etiologies or, if they have the same etiology, that the type of tumour depends on the age at which it develops.
KeywordsTesticular Cancer Material Handler Industry Group Stationary Engineer Germ Cell Cancer
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