Abstract
In the past decade, it has become increasingly clear that the mammalian skin harbors an indigenous population of lymphocytes, almost all of which belong to the T cell system (Stingi et al., 1989). In man, the majority of cutaneous T lymphocytes are found in the dermis, where they are preferentially clustered around postcapillary venules and around the appendages (Bos et al., 1987). Intraepidermal T cells account for only ≤ 10% of all T cells within human skin. In mice, the epidermis contains a regular network of T cells (Tschachler et al., 1983). Because of their characteristic morphology, they are referred to as Thy-1+ dendritic epidermal cells (Thy-1+ DEC) or, more recently, as dendritic epidermal T cells (DETC; Stingi et al., 1989).
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Stingl, G., Payer, E., Elbe, A. (1994). Ontogeny, Features and Functions of Epidermal T Lymphocytes. In: Lambert, W.C., Giannotti, B., van Vloten, W.A. (eds) Basic Mechanisms of Physiologic and Aberrant Lymphoproliferation in the Skin. NATO ASI Series, vol 265. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1861-7_2
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DOI: https://doi.org/10.1007/978-1-4615-1861-7_2
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