The Histological Spectrum of Cutaneous T-Cell Lymphoma
The term, cutaneous T-cell lymphoma, has been used to describe a variant of T-cell lymphoma with primary manifestations in the skin. Recent progress in techniques such as immunohistochemistry and molecular biology (Wood et al., 1986) has shown that cutaneous T-cell lymphoma is a heterogenous group, with many clinicopathological subsets (Slater, 1991). The diagnostic criteria for certain specific forms of cutaneous T-cell lymphoma are reviewed with an emphasis on the light microscopic appearances. The following entities are described: mycosis fungoides, Sézary syndrome, pagetoid reticulosis, HTLV-1 associated T-cell lymphoma, and CD30 positive lymphoproliferative disorders.
KeywordsLarge Cell Anaplastic Lymphoma Mycosis Fungoides Sezary Syndrome Cutaneous Lymphoma Lymphomatoid Granulomatosis
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