Skip to main content
SpringerLink
Log in
SpringerLink
Log in

Lipid Peroxidation and Diabetic Complications: Effect of Antioxidant Vitamins C and E

  • Chapter
Free Radicals in Diagnostic Medicine

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 366))

Abstract

There are 3 possible mechanisms for the pathogenesis of diabetic complications; sorbitol pathway, protein glycation and lipid peroxidation.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. J.A. Vinson, M.E. Staretz, P. Bose, H.M. Kassam, and B.S. Basalyga, In vitro and in vivo reduction of erythrocyte sorbitol by ascorbic acid, Diabetes 38, 1036 (1989).

    Article  PubMed  CAS  Google Scholar 

  2. P. Stolba, K. Hatle, A. Krnakova, M. Streda, and L. Starka, Effects of ascorbic acid on nonenzymatic glycation of serum proteins in vitro and in vivo, Diabetologia 30:585A (1987).

    Google Scholar 

  3. C. Ceriello, D. Giugliano, A. Quatraro, C. Donzella, G. Dipalo, and P.J. Lefebvre, Vitamin E reduction of protein glycosylation in diabetes, Diabetes Care 14:68 (1991).

    Article  PubMed  CAS  Google Scholar 

  4. S.A. Wohaieb and D.V. Godin, Alterations in free radical tissue-defense mechanisms in streptozocin-induced diabetes in rats. Diabetes 36:1014 (1987).

    Article  PubMed  CAS  Google Scholar 

  5. G. Gallou, A. Ruelland, B. Legras, D. Maugendre, H. Allannic and L. Cloarec, Clin. Chem. Acta 214:227 (1993).

    Article  CAS  Google Scholar 

  6. S.K. Jain, Hyperglycemia causes membrane lipid peroxidation and osmotic fragility in human red blood cells, J. Biol. Chem. 35:21340 (1989).

    Google Scholar 

  7. F. Simonelli, Lipid peroxidation is higher in human diabetic lens and cataractous lens than normal lens, Exp. Eye Res. 49:181 (1989).

    Article  PubMed  CAS  Google Scholar 

  8. J.A. Vinson, C.J. Possanza, and A.V. Drack, The effect of ascorbic acid on galactose-induced cataracts, Nutr. Repts. Intl. 33:665 (1986).

    CAS  Google Scholar 

  9. J.A. Vinson, J.M. Courey, and N.P. Maro, Comparison of two forms of vitamin C on galactose cataracts, Nutr. Res. 12:915 (1992).

    Article  CAS  Google Scholar 

  10. J.A. Vinson and C. Hsu, Effect of vitamins A, E and a citrus extract on in vitro and in vivo lipid peroxidation, Med. Sci. Res. 20:145 (1992).

    CAS  Google Scholar 

  11. W.R. Ross, M.O. Creighton, P.J. Stewart-DeHaan, M. Sanwal, M. Hirst and J.R. Trevithick, Can. J. Ophthalmol. 17:61 (1982).

    PubMed  CAS  Google Scholar 

  12. M.L. Bierenbaum, F.J. Noonan, L.J. Machlin, S. Machlin, A. Stier, P.B. Watson, A.M. Naso, and A.I. Fleischmann, The effect of supplemental vitamin E on serum parameters in diabetics, post coronary and normal subjects, Nutr. Repts. Intl. 31:1171 (1985).

    CAS  Google Scholar 

  13. G. Paolisso, A. D’Amore, D. Giugliano, A. Ceriello, M. Varricchio and F. D’Onofrio, Pharmacologic doses of vitamin E improve insulin action in healthy subjects and non-insulin-dependent diabetics, Am. J. Clin. Nutr. 57:650 (1993).

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Chemistry, University of Scranton, Scranton, PA, 18510, USA

    J. Vinson, C. Hsu, C. Possanza, A. Drack, D. Pane, R. Davis, C. Klock, K. Graser & X. Wang

Authors
  1. J. Vinson
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. C. Hsu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. C. Possanza
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. A. Drack
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. D. Pane
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. R. Davis
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. C. Klock
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. K. Graser
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. X. Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. State University of New York at Buffalo, Buffalo, New York, USA

    Donald Armstrong

Rights and permissions

Reprints and permissions

Copyright information

© 1994 Springer Science+Business Media New York

About this chapter

Cite this chapter

Vinson, J. et al. (1994). Lipid Peroxidation and Diabetic Complications: Effect of Antioxidant Vitamins C and E. In: Armstrong, D. (eds) Free Radicals in Diagnostic Medicine. Advances in Experimental Medicine and Biology, vol 366. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1833-4_42

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-1833-4_42

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5742-1

  • Online ISBN: 978-1-4615-1833-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation