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Lipid Peroxidation in Normal Pregnancy and Preeclampsia

  • Anna Cargnoni
  • Gina Gregorini
  • Claudio Ceconi
  • Rosario Maiorca
  • Roberto Ferrari
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 366)

Abstract

Increased levels of lipid peroxidation may contribute to the development of endothelial injury which is a key pathogenetic factor in preeclampsia1. Moreover, lipid peroxides per se inhibit prostacyclin formation without affecting thromboxane synthetic pathways2. In this way they could directly contribute to the generation of the thromboxaneprostacyclin imbalance reported in preeclampsia. Increased blood levels of lipid peroxidation products in preeclampsia have been reported by many authors2–4. Levels of lipid peroxidation were usually determined as malondialdehyde (MDA) content measured by the TBA-test.

Keywords

Lipid Peroxidation Uric Acid Serum Uric Acid Normal Pregnancy Lipid Peroxidation Product 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Anna Cargnoni
    • 1
  • Gina Gregorini
    • 2
  • Claudio Ceconi
    • 3
  • Rosario Maiorca
    • 2
  • Roberto Ferrari
    • 3
  1. 1.Fondazione Clinica del LavoroCentro di Fisiopatologia Cardiovascolare “S. Maugeri”Gussago, BresciaItaly
  2. 2.Chair of NephrologyUniversity of BresciaSpedali Civili, BresciaItaly
  3. 3.University of BresciaSpedali Civili, BresciaItaly

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