A New Method for Detecting Lipid Peroxidation by Using Dye Sensitized Chemiluminescence
Part of the
Advances in Experimental Medicine and Biology
book series (AEMB, volume 366)
It has been suggested that iron induced-microsomal lipid peroxidation produces at least two excited species; one for 1O2, and another for excited carbonyl(s), via splitting of a dimer of lipid peroxy radicals1. The carbonyls in excited triplet state are known to transfer their excitation energy to triplet sensitizers such as rose-bengal, eosin and 9:10-dibromoanthracene which have suitable molecular orbitals.
KeywordsLipid Peroxidation Excited Triplet State Chemiluminescence Method Singlet Ground State Excited Species
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K. Sugioka and M. Nakano, A possible mechanism of the generation of singlet molecular oxygen in NADPH-dependent microsomal lipid peroxidation. Biochim Biophys Acta 423:203 (1976).PubMedCrossRefGoogle Scholar
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