Free Radicals in Diagnostic Medicine pp 165-169 | Cite as
Lipid Peroxides in Hepatic, Gastrointestinal, and Pancreatic Diseases
Chapter
Abstract
Although the liver, stomach, intestine, and pancreas are classified in the same group, i.e., digestive organs, their functions are largely different from each other. In spite of such differences, it seems that injury to these organs could be commonly provoked by lipid peroxidation with a burst of free radical production in situ. Therefore, administration of antioxidants would be useful treatment and even prophylactic for such injury. Some topics related to these problems are described.
Keywords
Lipid Peroxide Acute Pancreatitis Sialic Acid Ellagic Acid Lipid Peroxide Level
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Preview
Unable to display preview. Download preview PDF.
References
- 1.T. Suematsu, T. Kamada, H. Abe, S. Kikuchi, and K. Yagi, Serum lipoperoxide level in patients suffering from liver diseases, Clin. Chim. Acta 79: 267 (1977).PubMedCrossRefGoogle Scholar
- 2.K. Yagi, A simple fluorometric assay for lipoperoxide in blood plasma, Biochem. Med. 15: 212 (1976).PubMedCrossRefGoogle Scholar
- 3.H. Ohkawa, N. Ohishi, and K. Yagi, Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction, Anal. Biochem. 95: 351 (1979).PubMedCrossRefGoogle Scholar
- 4.E. Maellaro, A. F. Casini, B. D. Bello, and M. Comporti, Lipid peroxidation and antioxidant systems in the liver injury produced by glutathione depleting agents, Biochem. Pharmacol. 39: 1513 (1990).PubMedCrossRefGoogle Scholar
- 5.I. Nishigaki, R. Kuttan, H. Oku, F. Ashoori, H. Abe, and K. Yagi, Suppressive effect of curcumin on lipid peroxidation induced in rats by carbon tetrachloride or 60Co-irradiation, J. Clin. Biochem. Nutr. 13: 23 (1992).CrossRefGoogle Scholar
- 6.T. Yoshikawa, N. Yoshida, H. Miyagawa, T. Takemura, T. Tanigawa, S. Sugino, and M. Kondo, Role of lipid peroxidation in gastric mucosal lesions induced by burn schock in rats, J. Clin. Biochem. Nutr. 2: 163 (1987).CrossRefGoogle Scholar
- 7.T. Yoshikawa, M. Yasuda, S. Ueda, Y. Naito, T. Tanigawa, H. Oyamada, and M. Kondo, Vitamin E in gastric mucosal injury induced by ischemia-reperfusion, Am. J. Clin. Nutr. 53: 210S (1991).PubMedGoogle Scholar
- 8.T. Yoshikawa, Y. Naito, S. Ueda, H. Ichikawa, S. Takahashi, M. Yasuda, and M. Kondo, Ischemiareperfusion injury and free radical involvement in gastric mucosal disorders, in: “Oxygen Transport to Tissue XIII”, T. K. Goldstick, M. McCabe, and D. J. Maguire, ed., Plenum Press, New York (1992).Google Scholar
- 9.T. Yoshikawa, H. Miyagawa, N. Yoshida, S. Sugino, and M. Kondo, Increase in lipid peroxidation in rat gastric mucosal lesions induced by water-immersion restraint stress, J. Clin. Biochem. Nutr. 1: 271 (1986).CrossRefGoogle Scholar
- 10.T. Yoshikawa, Y. Naito, S. Ueda, H. Oyamada, T. Takemura, N. Yoshida, S. Sugino, and M. Kondo, Role of oxygen-derived free radicals in the pathogenesis of gastric mucosal lesions in rats, J. Clin. Gastroenterol. 12(Suppl. 1): S65 (1990).PubMedCrossRefGoogle Scholar
- 11.T. Yoshikawa, Y. Naito, A. Kishi, T. Tomii, T. Kaneko, S. Iinuma, H. Ichikawa, M. Yasuda, S. Takahashi, and M. Kondo, Role of active oxygen, lipid peroxidation, and antioxidants in the pathogenesis of gastric mucosal injury induced by indomethacin in rats, Gut 34: 732 (1992).CrossRefGoogle Scholar
- 12.D. N. Granger, G. Rutili, and J. M. McCord, Superoxide radicals in feline intestinal ischemia, Gastroenterol. 81: 22 (1981).Google Scholar
- 13.A. Keshavarzian, G. Morgan, S. Sedghi, J. H. Gordon, and M. Doria, Role of reactive oxygen metabolites in experimental colitis, Gut 31: 786 (1990).PubMedCrossRefGoogle Scholar
- 14.C. F. Babbs, Free radicals and the etiology of colon cancer, Free Radical Biol. Med. 8: 191 (1990).CrossRefGoogle Scholar
- 15.H. Sanfey, G. B. Bulkley, and J. L. Cameron, The pathogenesis of acute pancreatitis. The source and role of oxygen-derived free radicals in three different experimental models, Ann. Surg. 201: 633 (1985).PubMedCrossRefGoogle Scholar
- 16.M. H. Schoenberg, M. Büchler, M. Gaspar, A. Stinner, M. Younes, I. Melzner, B. Bültman, and H. G. Beger, Oxygen free radicals in acute pancreatitis of the rat, Gut 31: 1138 (1990).PubMedCrossRefGoogle Scholar
- 17.M. H. Schoenberg, M. Büchlcr, M. Helfen, and H. G. Beger, Role of oxygen radicals in experimental acute pancreatitis, Eur. Surg. Res. 24: 74 (1992).PubMedCrossRefGoogle Scholar
- 18.Y. Morita, The role of oxygen-derived free radicals in the pathogenesis of cerulein-induced pancreatitis in rats, J. Kyoto Pref. Univ. Med. 101: 81 (1992).Google Scholar
Copyright information
© Springer Science+Business Media New York 1994