Abstract
Liposomes provide a carrier function to bring antigen to cells of the immune system and to provide a mechanism for slow release of antigen. Since liposomes are slowly absorbed, they also provide a “depot effect” in which the presence of the antigen may be maintained for a longer period of time compared to soluble antigen (Alving, 1991). In addition to antigen, liposomes may carry other agents that potentiate an immune response. In this chapter we will present our current data concerning the adjuvant effect of a special type of liposomes containing a subunit protein antigen and cytokines.
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Lachman, L.B., Shih, LC.N., Rao, XM., Ullrich, S.E., Cleland, J.L. (1995). Cytokine-Containing Liposomes as Adjuvants for Subunit Vaccines. In: Powell, M.F., Newman, M.J. (eds) Vaccine Design. Pharmaceutical Biotechnology, vol 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1823-5_29
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DOI: https://doi.org/10.1007/978-1-4615-1823-5_29
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