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Cell cycle control of DNA replication

  • Rati Fotedar
  • Arun Fotedar
Part of the Progress in Cell Cycle Research book series (PCCR)

Abstract

The cell cycle is driven by the sequential activation of a family of cyclin-dependent kinases (cdk), which phosphorylate and activate proteins that execute events critical to cell cycle progression. In mammalian cells cdk2-cyclin A has a role in S phase. Many replication proteins are potential substrates for this cdk kinase, suggesting that initiation, elongation and checkpoint control of replication could all be regulated by cdk2. The association of PCNA, a replication protein, with cdk-cyclins during G-1 to S phase transition and with cdk-cyclin inhibitors, adds an interesting complexity to regulation of DNA replication.

Keywords

Proliferate Cell Nuclear Antigen Replication System Replication Protein Initiator Protein Type Cyclins 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Diller, J.D. and Raghuraman, M.K. (1994) TIBS 19, 320–325.PubMedGoogle Scholar
  2. 2.
    Coverly, D. and Laskey, R.L. (1994) Annu. Rev. Biochem. 63, 745–776.CrossRefGoogle Scholar
  3. 3.
    Heichman, K.A. and Roberts, J.M. (1994) Cell 79, 557–562.PubMedCrossRefGoogle Scholar
  4. 4.
    Li, J.J. and Kelly, T.J. (1984) Proc. Natl. Acad. Sci. USA 81, 6973–6977.PubMedCrossRefGoogle Scholar
  5. 5.
    Stillman, B. and Gluzman, Y. (1985) Mol. Cell. Biol. 5, 2051–2060.PubMedGoogle Scholar
  6. 6.
    Wobbe, C.R., Dean, F.B., Weissbach, L. and Hurwitz, J. (1985) Proc. Natl. Acad. Sci. USA 82, 5710–5714.PubMedCrossRefGoogle Scholar
  7. 7.
    Hurwitz, J., Dean, F.B., Kwong, A.D. and Lee, S.-H. (1990). J. Biol. Chem. 265, 18043–18046.PubMedGoogle Scholar
  8. 8.
    Stillman, B. (1994) J. Biol. Chem. 269, 7047–7050.PubMedGoogle Scholar
  9. 9.
    Stillman, B. (1994) Cell 78, 725–728.PubMedCrossRefGoogle Scholar
  10. 10.
    Ryder, K., Silver, S., DeLucia, A.L., Fanning, E. and Tegtmeyer, P. (1986) Cell 44, 719–725.PubMedCrossRefGoogle Scholar
  11. 11.
    Deb, S., DeLucia, A., Koff, A., Tsui, S., and Tegtmeyer, P. (1986) Mol. Cell. Biol. 6, 4578–4584.PubMedGoogle Scholar
  12. 12.
    Borowiec, J.A. and Hurwitz, J. (1988) EMBO J. 7, 3149–3158.PubMedGoogle Scholar
  13. 13.
    Borowiec, J.A., Dean, F.B., Bullock, P.A. and Hurwitz, J. (1990) Cell 60, 181–184.PubMedCrossRefGoogle Scholar
  14. 14.
    Stahl, H., Dröge, P. and Knippers R. (1986) EMBO J. 5, 1939–1944.PubMedGoogle Scholar
  15. 15.
    Dean, F.B. and Hurwitz, J. (1991) J. Biol. Chem. 266, 5062–5071.PubMedGoogle Scholar
  16. 16.
    Fairman, M.P. and Stillman, B. (1988) EMBO J. 7, 1211–1218.PubMedGoogle Scholar
  17. 17.
    Wold, M.S. and Kelly, T.J. (1988) Proc. Natl. Acad. Sci. USA 85, 2523–2527.PubMedCrossRefGoogle Scholar
  18. 18.
    Kenny, M.K., Lee, S-H. and Hurwitz, J. (1989) Proc. Natl. Acad. Sci. USA 86, 9757–9761.PubMedCrossRefGoogle Scholar
  19. 19.
    Tsurimoto, T. and Stillman, B. (1989) EMBO J. 8, 3883–3889.PubMedGoogle Scholar
  20. 20.
    Kenny, M.K., Schlegel, U., Furneaux, H. and Hurwitz, J. (1990) J. Biol. Chem. 265, 7693–7700.PubMedGoogle Scholar
  21. 21.
    Mastrangelo, I.A., Hough, P.V.C., Wall, J.S., Dodson, M., Dean, F.B. and Hurwitz, J. (1989) Nature 338, 658–662.PubMedCrossRefGoogle Scholar
  22. 22.
    Fanning, E. and Knippers, R. (1992) Annu. Rev. Bioch. 61, 55–85.CrossRefGoogle Scholar
  23. 23.
    Scheidtmann, K.H. (1986) Virology 150, 85–95.PubMedCrossRefGoogle Scholar
  24. 24.
    McVey, D., Brizuela, L., Mohr, I., Marshak, D.R., Gluzman, Y. and Beach, D. (1989) Nature 341, 503–507.PubMedCrossRefGoogle Scholar
  25. 25.
    McVey, D., Ray, S., Gluzmann, Y., Berger, L., Wildeman, A.G., Marshak, D.R. and Tegtmeyer, P. (1993) J. Virol. 67, 5206–5216.PubMedGoogle Scholar
  26. 26.
    Cegielska, A. and Virshup, D.M. (1993) Mol. Cell Biol. 13, 1202–1211.PubMedGoogle Scholar
  27. 27.
    Georgaki, A. and Hubscher, U. (1993) Nucleic Acids Res. 21, 3659–3665.PubMedCrossRefGoogle Scholar
  28. 28.
    Erdile, L.F., Wold, M.S. and Kelly, T.J. (1990) J. Biol. Chem. 265, 3177–3182.PubMedGoogle Scholar
  29. 29.
    Erdile, L.F., Heyer, W-D., Kolodner, R. and Kelly, T.J. (1991) J. Biol. Chem. 266, 12090–12098.PubMedGoogle Scholar
  30. 30.
    Umbricht, C.B., Erdile, L.F., Jabs, E.W. and Kelly, T.J. (1993) J. Biol. Chem. 268, 6131–6138.PubMedGoogle Scholar
  31. 31.
    Henricksen, L.A., Umbricht, C.B. and Wold, M.S. (1994) J. Biol. Chem. 269, 11121–11132.PubMedGoogle Scholar
  32. 32.
    Stigger, E., Dean, F.B., Hurwitz, J. and Lee, S-H. (1994) Proc. Natl. Acad. Sci. USA 91, 579–583.PubMedCrossRefGoogle Scholar
  33. 33.
    Heyer, W-D., Rao, M.R.S., Erdile, L.F., Kelly, T.J. and Kolodner, R.D. (1990) EMBO J. 9, 2321–2329.PubMedGoogle Scholar
  34. 34.
    Brill, S.J. and Stillman, B. (1989) Nature 342, 92–95.PubMedCrossRefGoogle Scholar
  35. 35.
    Brill, S.J. and Stillman, B. (1991) Genes Dev. 5, 1589–1600.PubMedCrossRefGoogle Scholar
  36. 36.
    Fang, F. and Newport, J.W. (1993) J. Cell Sci. 106, 983–994.PubMedGoogle Scholar
  37. 37.
    Dornreiter, I., Erdile, L.F., Gilbert, I.U., Winkler, D., Kelly, T.J. and Fanning, E. (1992) EMBO J. 11, 769–776.PubMedGoogle Scholar
  38. 38.
    Longhese, M.P., Plevani, P. and Lucchini, G. (1994) Mol. Cell. Biol. 14, 7884–7890.PubMedGoogle Scholar
  39. 39.
    Yang, L., Li, R.L., Mohr, I.J., Clark, R. and Botchan, M.L. (1991) Nature 353, 628–632.PubMedCrossRefGoogle Scholar
  40. 40.
    Muller, F., Seo, Y.-S. and Hurwitz, J. (1994) J. Biol. Chem. 269, 17086–17094.PubMedGoogle Scholar
  41. 41.
    DePamphilis, M.L. (1993) Annu. Rev. Biochem. 62, 29–63.PubMedCrossRefGoogle Scholar
  42. 42.
    Almouzni, G., and Wolffe, A.P. (1993) Exp. Cell Res. 205, 1–15.PubMedCrossRefGoogle Scholar
  43. 43.
    Adachi, Y. and Laemmli, U.K. (1992) J. Cell Biol. 119, 1–15.PubMedCrossRefGoogle Scholar
  44. 44.
    Rowley, A., Dowell, S.J. and Diffley, J.F.X. (1994). Biochemica et Biophysica Acta 1217, 239–256.CrossRefGoogle Scholar
  45. 45.
    Bell, S.P. and Stillman, B. (1992) Nature 357, 128–134.PubMedCrossRefGoogle Scholar
  46. 46.
    Diffley, J.F.X. and Cocker, J.H. (1992) Nature 357, 169–172.PubMedCrossRefGoogle Scholar
  47. 47.
    Huberman, J.A. (1994) Nature 367, 20–21.PubMedCrossRefGoogle Scholar
  48. 48.
    Bell, S.P., Kobayashi, R. and Stillman, B. (1993) Science 262, 1844–1870.PubMedCrossRefGoogle Scholar
  49. 49.
    Micklem, G., Rowley, A., Harwood, J., Nasymth, K and Diffley, J. F. X. (1993). Nature. 366, 87–89.PubMedCrossRefGoogle Scholar
  50. 50.
    Diffley, J.F.X., Cocker, J.H., Dowell, S.J. and Rowley, A. (1994) Cell, 78, 303–316.PubMedCrossRefGoogle Scholar
  51. 51.
    Melendy, T. and Stillman, B. (1993) J. Biol. Chem. 268, 3389–3395.PubMedGoogle Scholar
  52. 52.
    Murakami, Y. and Hurwitz, J. (1993) J. Biol. Chem. 268, 11008–11017.PubMedGoogle Scholar
  53. 53.
    Tsurimoto, T., Fairman, M. and Stillman, B. (1989) Mol. Cell. Biol. 9, 3839–3849.PubMedGoogle Scholar
  54. 54.
    Tsurimoto, T., Melendy, T. and Stillman, B. (1990) Nature 346, 543–539.CrossRefGoogle Scholar
  55. 55.
    Lee, S.-H., Kwong, A.D., Pan, Z-Q. and Hurwitz, J. (1991) J. Biol. Chem. 266, 594–602.PubMedGoogle Scholar
  56. 56.
    Tsurimoto, T. and Stillman, B. (1991) J. Biol. Chem. 266, 1950–1960.PubMedGoogle Scholar
  57. 57.
    Tsurimoto, T. and Stillman, B. (1991) J. Biol. Chem. 266, 1961–1968.PubMedGoogle Scholar
  58. 58.
    Waga, S., Baeur, G. and Stillman, B. (1994) J. Biol. Chem. 269, 10923–10934PubMedGoogle Scholar
  59. 59.
    Wang, T.S.-F. (1991) Annu. Rev. Biochem. 60, 513–552.PubMedCrossRefGoogle Scholar
  60. 60.
    Izumi, M., Miyazawa, H., Harakawa, S., Yatagai, F. and Hanaoka F. (1994) J. Biol. Chem. 269, 7639–7644.PubMedGoogle Scholar
  61. 61.
    Tan, C.-K., Castillo, C., So, A.G. and Downey, K.M. (1986) J. Biol. Chem. 261, 12310–12316.PubMedGoogle Scholar
  62. 62.
    Prelich, G., Tan, C-K., Kostura, M., Mathews, M.B., So, A.G., Downey, K.M. and Stillman, B. (1987) Nature 326, 517–520.PubMedCrossRefGoogle Scholar
  63. 63.
    Produst, V.N. and Hubscher, U. (1993) Nucleic Acids Res. 21, 841–846.CrossRefGoogle Scholar
  64. 64.
    Lee, S-H., Eki, T. and Hurwitz, J. (1989) Proc. Natl. Acad. Sci. 86, 7361–7365.PubMedCrossRefGoogle Scholar
  65. 65.
    Weinberg, D.H., Collins, K.L., Simancek, P., Russo, A., Wold, M.S., Virshup, D.M. and Kelly, T.J. (1990) Proc.Natl. Acad. Sci. 87, 8692–8696.PubMedCrossRefGoogle Scholar
  66. 66.
    Tsurimoto, T. and Stillman, B. (1990) Proc. Natl. Acad. Sci. USA 87, 1023–1027.PubMedCrossRefGoogle Scholar
  67. 67.
    Bunz, F., Kobayashi, R. and Stillman, B. (1993). Proc. Natl. Acad of Sci. 90, 11014–11018.CrossRefGoogle Scholar
  68. 68.
    Burbelo, P.D., Utani, A., Pan, Z-Q. and Yamada, Y. (1993). Proc. Natl. Acad. Sci. 90, 11543–11547.PubMedCrossRefGoogle Scholar
  69. 69.
    Luckow, B., Bunz, F., Stillman, B., Lichter, P. Schütz, G. (1994) Mol. Cell. Biol. 14, 1626–1634.PubMedGoogle Scholar
  70. 70.
    Chen, M., Pan, Z-Q. and Hurwitz J. (1992) Proc. Natl. Acad. Sci. USA 89, 2516–2520.PubMedCrossRefGoogle Scholar
  71. 71.
    Chen, M., Pan, Z-Q. and Hurwitz J. (1992) Proc. Natl. Acad. Sci. USA 89, 5211–5215.PubMedCrossRefGoogle Scholar
  72. 72.
    O’Donnell, M., Onrust, R., Dean, F.B., Chen, M. and Hurwitz, J. (1993) Nucleic Acids Res. 21, 1–3.CrossRefGoogle Scholar
  73. 73.
    Pan, Z-Q, Chen, M. and Hurwitz, J. (1993) Proc. Natl. Acad. Sci. 90, 6–10.PubMedCrossRefGoogle Scholar
  74. 74.
    Bravo, R. and Celis, J.E. (1978) J. Cell Biol. 84, 795–802.CrossRefGoogle Scholar
  75. 75.
    Mathews, M.B., Bernstein, R.M., Franza, B.R. and Garreis, J.I. (1984) Nature 309, 374–376.PubMedCrossRefGoogle Scholar
  76. 76.
    Kuriyan, J and O’Donnell, M. (1993) J. Mol. Biol. 234, 915–925.PubMedCrossRefGoogle Scholar
  77. 77.
    Kong, X.-P., Onrust, R., O’Donnell, M., and Kuryan, J. (1992) Cell 69, 425–437.PubMedCrossRefGoogle Scholar
  78. 78.
    Krishna, T.S.R., Kong, X-P., Gary, S., Burgers, P., and Kuriyan, J. (1994) Cell 79, 1233–1243.PubMedCrossRefGoogle Scholar
  79. 79.
    Campbell, J.L. (1993) J. Biol. Chem. 268, 25261–25264.PubMedGoogle Scholar
  80. 80.
    Johnson, L.M., Snyder, M., Chang, L.M.S., Davis, R.L. and Campbell, J.L. (1985) Cell 43, 369–377.PubMedCrossRefGoogle Scholar
  81. 81.
    Pizzagalli, A., Valsasnini, P., Plevani, P. and Lucchini, G. (1988) Proc. Natl. Acad. Sci. USA 85, 3772–3776.PubMedCrossRefGoogle Scholar
  82. 82.
    Bauer, G.A., Heller, H.M. and Burgers, P.M.J. (1988) J. Biol. chem. 263, 917–924.PubMedGoogle Scholar
  83. 83.
    Boulet, A., Simon, M., Faye, G., Bauer, G.A. and Burgers, P.M.J. (1989) EMBO J. 8, 1849–1854.PubMedGoogle Scholar
  84. 84.
    Sitney, K.C., Budd, M.E. and Campbell, J.L. (1989) Cell 56, 599–605.PubMedCrossRefGoogle Scholar
  85. 85.
    Araki, H., Roop, P.A. Johnson, A.L., Johnston, L.H., Morrison, A., and Sugino, A. (1992). EMBO J. 11, 733–740.PubMedGoogle Scholar
  86. 86.
    Morrison, A., Araki, H., Clark, A.B., Hamatake, R.K. and Sugino, A. (1990) Cell 62, 1143–1151.PubMedCrossRefGoogle Scholar
  87. 87.
    Bauer, G.A. and Burgers, P.M.J. (1988). Proc. Natl. Acad. Sci. USA 85, 7506–7510.PubMedCrossRefGoogle Scholar
  88. 88.
    Bauer, G.A. and Burgers, P.M.J. (1990). Nucleic Acids Res. 18, 261–265.PubMedCrossRefGoogle Scholar
  89. 89.
    Yoder, B.L. and Burgers, P.M.J. (1991) J. Biol. Chem. 266, 22689–22697.PubMedGoogle Scholar
  90. 90.
    Fien, K., and Stillman, B. (1992) Mol. Cell. Biol. 12, 155–163.PubMedGoogle Scholar
  91. 91.
    Howell, E. A., McLear, M.A., David, R. and Holm, C. (1994) Mol. Cell. Biol. 14, 255–267.PubMedGoogle Scholar
  92. 92.
    Andrews, B.J. and Herskowitz, I. (1990) J. Biol. Chem. 265, 14057–14060.PubMedGoogle Scholar
  93. 93.
    Lowndes, N.F., Johnson, A. L. and Johnston, L. H. (1991) Nature 350, 247–250.PubMedCrossRefGoogle Scholar
  94. 94.
    Hartwell, L.H. (1974) Bacteriol. Rev. 38, 164–198.PubMedGoogle Scholar
  95. 95.
    Pardee, A.B. (1974) Proc. Natl. Acad. Sci. USA 71, 1286–1290.PubMedCrossRefGoogle Scholar
  96. 96.
    Beach, D., Durkacz, B. and Nurse, P. (1982) Nature 300, 706–709.PubMedCrossRefGoogle Scholar
  97. 97.
    Reed, S.I. (1992) Annu. Rev. Cell Biol. 8, 529–561.PubMedCrossRefGoogle Scholar
  98. 98.
    Paris, J., LeGuellec, R., Cauturier, A., LeGuellec, K., Omilli, F., Camonis, J., MacNeill, S. and Philippe, M. (1991) Proc. Natl. Acad. Sci. USA 88, 1039–1043.PubMedCrossRefGoogle Scholar
  99. 99.
    Tsai, L-H., Harlow, E. and Meyerson, M. (1991) Nature 353, 174–177.PubMedCrossRefGoogle Scholar
  100. 100.
    Meyerson, M., Enders, G.H., Wu, C-L., Su, L-K., Gorka, C., Nelson, C., Harlow, E. and Tsai, L-H. (1992) EMBO J. 11, 2909–2917.PubMedGoogle Scholar
  101. 101.
    Pines, J. (1993) TIBS 18, 195–197.PubMedGoogle Scholar
  102. 102.
    Pagano, M., Pepperkok, R., Lukas, J., Baldin, V., Ansorge, W., Bartek, J. and Draetta, G. (1993) J. Cell. Biol. 121, 101–111.PubMedCrossRefGoogle Scholar
  103. 103.
    Tsai, L.-H., Lees, E., Faha, B., Harlow, E. and Riabowol, K. (1993) Oncogene 8, 1593–1602.PubMedGoogle Scholar
  104. 104.
    Th’ng, J.P.H., Wright, P.S., Hamaguchi, J., Lee, M.G., Norbury, C.J., Nurse, P. and Bradbury, E.M. (1990) Cell 63, 313–324.CrossRefGoogle Scholar
  105. 105.
    van den Heuvel, S. and Harlow, E. (1994) Science 262, 2050–2054.CrossRefGoogle Scholar
  106. 106.
    Sherr, C.J. (1994) Cell 79, 551–555.PubMedCrossRefGoogle Scholar
  107. 107.
    Quelle, D.E., Ashmun, R.A., Shurtleff, S.A., Kato, J.-Y., Bar-Sagi, D., Roussel, M.F. and Sherr, C.-J. (1993) Genes Dev. 7, 1559–1571.PubMedCrossRefGoogle Scholar
  108. 108.
    Resnitzky, D., Gossen, M., Bujard, H. and Reed, S.I. (1994). Mol. Cell. Biol. 14, 1669–1679.PubMedGoogle Scholar
  109. 109.
    Ohtsubo, M. and Roberts, J.M. (1993) Science 259, 1908–1912.PubMedCrossRefGoogle Scholar
  110. 110.
    Wimmel, A., Lucibello, F.C., Sewing, A., Adolph, S. and Muller, R. (1994) Oncogene 9, 995–997.PubMedGoogle Scholar
  111. 111.
    Wang, J., Zindy, F., Chenivesse, X., Lamas, E., Henglein, B and Brechot, C. (1992) Oncogene 7, 1653–1656.PubMedGoogle Scholar
  112. 112.
    Glotzer, M., Murray, A.W. and Kirschner, M.W. (1991) Nature 349, 132–138.PubMedCrossRefGoogle Scholar
  113. 113.
    Baldin, V., Lukas, J., Marcote, M.J., Pagano, M. and Draetta, G. (1993) Genes Dev. 7, 812–821.PubMedCrossRefGoogle Scholar
  114. 114.
    Girard, F., Strausfeld, U., Fernandez, A. and Lamb, N.J.C. (1991) Cell 67, 1169–1179.PubMedCrossRefGoogle Scholar
  115. 115.
    Pagano, M., Pepperkok, R., Verde, F., Ansorge, W. and Draetta, G. (1992) EMBO J. 11, 961–971.PubMedGoogle Scholar
  116. 116.
    Zindy, F., Lamois, E., Chenivesse, X., Sobczak, J., Wang, J., Fesquet, D., Henglein, B. and Bréchot, C. (1992) Biochem. Biophys. Res. Commun. 182, 1144–1154.PubMedCrossRefGoogle Scholar
  117. 117.
    Knoblich, J.A., Sauer, K., Jones, L., Richardson, H., Saint, R. and Lehner, C.F. (1994) Cell 77, 1–20.CrossRefGoogle Scholar
  118. 118.
    Pines, J. and Hunter, T. (1990) Nature 346, 760–763.PubMedCrossRefGoogle Scholar
  119. 119.
    Pagano, M., Draetta, G. and Jansen-Durr, P. (1992) Science 254, 1144–1147.CrossRefGoogle Scholar
  120. 120.
    Rosenblatt, J., Gu, Y. and Morgan, D.O. (1992) Proc. Natl. Acad. Sci. USA 89, 2824–2828.PubMedCrossRefGoogle Scholar
  121. 121.
    Epstein, C.B. and Cross, F.R. (1992) Genes Dev. 6, 1695–1706.PubMedCrossRefGoogle Scholar
  122. 122.
    Schwob, E. and Nasmyth, K. (1993) Genes Dev. 7, 1160–1175.PubMedCrossRefGoogle Scholar
  123. 123.
    Russell, P. and Nurse, P. (1987) Cell 49, 559–567.PubMedCrossRefGoogle Scholar
  124. 124.
    Parker, L.L. and Piwnica-Worms, H. (1992) Science, 257, 1955–1957.PubMedCrossRefGoogle Scholar
  125. 125.
    Fesquet, D., Labbé, J-C., Derancourt, J., Capony, J-P., Galas, S., Girad, F., Lorca, T., Shuttleworth, J., Dorée, M. and Cavadore, J-C. (1993) EMBO J. 12, 3111–3121.PubMedGoogle Scholar
  126. 126.
    Poon, R.Y.C., Yamashita, K., Adamczewki, J.P., Hunt, T. and Shuttleworth, J. (1993) EMBO J. 12, 3123–3132.PubMedGoogle Scholar
  127. 127.
    Solomon, M.J., Harper, J.W. and Shuttleworth, J. (1993) EMBO J. 12, 3133–3142.PubMedGoogle Scholar
  128. 128.
    Fisher, R.P. and Morgan, D.O. (1994) Cell 78, 713–724.PubMedCrossRefGoogle Scholar
  129. 129.
    Mäkelä, T. M., Tassan, J-P., Nigg, E.A., Frutiger, S., Hughes, G.J. and Weinberg, R.A. (1994) Nature 371, 254–257.PubMedCrossRefGoogle Scholar
  130. 130.
    Dunphy, W.G. and Kumagai, A. (1991) Cell 67, 189–196.PubMedCrossRefGoogle Scholar
  131. 131.
    Millar, J.B.A., Blevitt, J., Gerace, L., Sadhu, K., Featherstone, C. and Russel. P. (1991) Proc. Natl. Acad. Sci. USA 88, 10500–10504.PubMedCrossRefGoogle Scholar
  132. 132.
    Coleman, T.R. and Dunphy, W.G. (1994) Curr.Opin.Cell Biol. 6, 877–882.PubMedCrossRefGoogle Scholar
  133. 133.
    Clarke, P.R. (1995) Curr. Biol. 5, 40–42.PubMedCrossRefGoogle Scholar
  134. 134.
    Elledge, S.J. and Harper, J.H. (1994) Curr. Opin. Cell Biol. 6, 847–852.PubMedCrossRefGoogle Scholar
  135. 135.
    Hunter, T. and Pines J. (1994) Cell 79, 573–582.PubMedCrossRefGoogle Scholar
  136. 136.
    Peter, M. and Herskowitz, I. (1994) Cell 79, 181–184.PubMedCrossRefGoogle Scholar
  137. 137.
    Gu, Y., Turck, C.W. and Mogan, D. (1993) Nature 366, 707–710.PubMedCrossRefGoogle Scholar
  138. 138.
    Harper, J.W., Adami, G.R., Wei, N., Keyomarsi, K. and Elledge, S.J. (1993) Cell 75, 805–816.PubMedCrossRefGoogle Scholar
  139. 139.
    Xiong, Y., Hannon, G.J., Zhang, H., Casso, D., Kobayashi, R. and Beach, D. (1993) Nature 366, 701–704.PubMedCrossRefGoogle Scholar
  140. 140.
    Noda, A., Ning, Y., Venable, S.F., Pereira-Smith, O.M. and Smith, J. (1994) Exp. Cell Res. 211, 90–98.PubMedCrossRefGoogle Scholar
  141. 141.
    El-Diery, W.S., Tokino, T., Velculescu, V.E., Levy, D.B., Parsons, R., Trent, J.M., Lin, D., Mercer, E., Kinzler, K.W. and Vogelstein, B. (1993) Cell 75, 817–825.CrossRefGoogle Scholar
  142. 142.
    Polyak, K., Lee, M-H., Erdjument-Bromage, H., Koff, A., Roberts, J.M., Tempst, P. and Massague, J. (1994) Cell 78, 59–66.PubMedCrossRefGoogle Scholar
  143. 143.
    Toyoshima, H., and Hunter, T. (1994) Cell 78, 67–74.PubMedCrossRefGoogle Scholar
  144. 144.
    Fotedar, R., Fitzgerald, P., Rousselle, T., Cannella, D., Messier, H. and Fotedar, A. (1995) Submitted.Google Scholar
  145. 145.
    Guan, K-L, Jenkins, C.W., Li, Y., Nichols, M.A., Wu, X., O’Keefe, C.L., Matera, A.G. and Xiong, Y. (1994) Genes Dev. 8, 2939–2952.PubMedCrossRefGoogle Scholar
  146. 146.
    Hannon, G.J. and Beach, D. (1994) Nature 371, 257–261.PubMedCrossRefGoogle Scholar
  147. 147.
    Serrano, M., Hannon, G.J. and Beach, D. (1993) Nature 366, 704–707.PubMedCrossRefGoogle Scholar
  148. 148.
    Weinberg, R. (1993) Neuron 11, 191–196.PubMedCrossRefGoogle Scholar
  149. 149.
    Nevins, J.R. (1992) Nature 358, 375–376.PubMedCrossRefGoogle Scholar
  150. 150.
    Matsushime, H., Quelle, D.E., Shurtleff, S.A., Shibuya, M., Sherr, C.J. and Kato, J.-Y. (1994) Mol. Cell. Biol. 14, 2066–2076.PubMedGoogle Scholar
  151. 151.
    Meyerson, M. and Harlow, E. (1994) Mol. Cell. Biol. 14, 2077–2086.PubMedGoogle Scholar
  152. 152.
    Kamb, A., Gruis, N.A., Weaver-Feldhaus, J., Liu, Q., Harshman, K., Tavtigian S.V., Stockert, E., Day, R.S., Johnson, B.E. and Skolnick, M.H. (1994) Science 264, 436–440.PubMedCrossRefGoogle Scholar
  153. 153.
    Shaeff, R.J. and Roberts, J.M. (1995) Current Biology 5, 28–31.CrossRefGoogle Scholar
  154. 154.
    Fornace, A.J. (1992) Annu. Rev. Gent. 26, 507–526.CrossRefGoogle Scholar
  155. 155.
    Dulic, V., Kaufman, W.K., Wilson, S., Tisty, T.D., Lees, E., Harper, J.W., Elledge, S.J. and Reed, S.I. (1994) Cell 76, 1013–1023.PubMedCrossRefGoogle Scholar
  156. 156.
    Okamoto, K. and Beach, D. (1994) EMBO J. 13, 4816–4822.PubMedGoogle Scholar
  157. 157.
    Kastan, M.B., Zhan, Q., El-Deiry, W.S., Carrier, F., Jacks, T., Walsh, V. W., Plunkett, B.S., Vogelstein, B. and Fornace, A.J. (1992) Cell 71, 587–597.PubMedCrossRefGoogle Scholar
  158. 158.
    Smith, M.L. Chen, I-T., Zhan, Q., Bae, I., Chen, C-Y., Gilmer, T.M., kastan, M.B., O’Conner, P.M. and Fornace, A.J. Jr. (1994) Science 266, 1376–1380.PubMedCrossRefGoogle Scholar
  159. 159.
    Coverley, D., Kenny, M.K., Munn, M., Rupp, W.D., Lane, D.P. and Wood, R.D. (1991) Nature, 349, 538–541.PubMedCrossRefGoogle Scholar
  160. 160.
    Shivji, M.K.K., Kenny, M.K. and Wood, R.D. (1992) Cell 69, 367–374.PubMedCrossRefGoogle Scholar
  161. 161.
    Waga, S., Hannon, G.J., Beach, D. and Stillman, B. (1994). Nature 369, 574–578.PubMedCrossRefGoogle Scholar
  162. 162.
    Flores-Rozas, H., Kelman, Z., Dean, F.B., Pan, Z-Q, Harper, J.W., Elledge, S.J., O’Donnell, M and Hurwitz, J. (1994) Proc. Natl. Acad. Sci. 91, 8655–8659.PubMedCrossRefGoogle Scholar
  163. 163.
    Strausfeld, U.P., Howell, M., Rempel, R., Maller, J.L., Hunt, T. and Blow, J.J. (1994) Current Biol. 4, 876–883.CrossRefGoogle Scholar
  164. 164.
    Wang, Z., Wu, X. and Friedberg, E.C. (1993) Mol. Cell. Biol. 13, 1051–1058.PubMedGoogle Scholar
  165. 165.
    Rao, P.N. and Johnson, R.T. (1970) Nature 225, 159–164.PubMedCrossRefGoogle Scholar
  166. 166.
    Rao, P.N., Sunkara, P.S. and Wilson, B.A. (1977) Proc. Natl. Acad. Sci. USA 74, 2869–2873.PubMedCrossRefGoogle Scholar
  167. 167.
    Rossow, P.W., Riddle, V.G.H. and Pardee, A.B. (1979) Proc. Natl. Acad. Sci. USA 76, 4446–4450.PubMedCrossRefGoogle Scholar
  168. 168.
    Wong, S.W., Paborsky, L.R., Fisher, P.A., Wang, T.S.-F. and Korn, D. (1986) J. Biol. Chem. 261, 7958–7968.PubMedGoogle Scholar
  169. 169.
    Roberts, J.M. and D’Urso, G. (1988) Science 241, 1486–1489.PubMedCrossRefGoogle Scholar
  170. 170.
    Morris, G.F. and Mathews, M.B. (1989) J. Biol. Chem. 264, 13856–13864.PubMedGoogle Scholar
  171. 171.
    Din, S-U., Brill, S.J., Fairman, M.P. and Stillman, B. (1990) Genes Dev. 4, 968–977.PubMedCrossRefGoogle Scholar
  172. 172.
    Brenot-Bosc, F., Gupta, S., Margolis, R.L., and Fotedar, R. (1995). Chromosoma 103, 517–527.PubMedCrossRefGoogle Scholar
  173. 173.
    Cardoso, M.C., Leonhardt, H. and Nadal-Ginard, B. (1993) Cell 74, 979–992.PubMedCrossRefGoogle Scholar
  174. 174.
    Fotedar, R. and Roberts, J.M. (1992) EMBO J. 11, 2177–2187.PubMedGoogle Scholar
  175. 175.
    Bravo, R. and Macdonald-Bravo, H. (1987). J. Cell Biology 105, 1549–1554.CrossRefGoogle Scholar
  176. 176.
    Pines, J. and Hunter, T. (1991) J. Cell Biol. 115, 1–17.PubMedCrossRefGoogle Scholar
  177. 177.
    Fotedar, R. and Roberts, J.M. (1991) Cold Spring Harbor Symp. Quant. Biol. LVI, 325–333.CrossRefGoogle Scholar
  178. 178.
    Sobczak-Thepot, J., Harper, F., Florentin, Y., Zindy, F., Bréchot, C. and Puvion, E. (1993). Exp. Cell Res. 206, 43–48.PubMedCrossRefGoogle Scholar
  179. 179.
    Lukas, J., Pagano, M., Staskova, Z., Draetta, G. and Bartek, J. (1994). Oncogene 9, 707–718.PubMedGoogle Scholar
  180. 180.
    Xiong, Y., Zhang, H. and Beach, D. (1992) Cell 71, 504–514.CrossRefGoogle Scholar
  181. 181.
    Matsuoko, S., Yamaguchi, M. and Matsukage, A. (1994) J. Biol. Chem. 269, 11030–11036.Google Scholar
  182. 182.
    Maridor G., Gallant. P., Golsteyn. R. and Nigg, E.A. (1993) J. Cell Sci. 106, 535–544.PubMedGoogle Scholar
  183. 183.
    Wobbe, C.R. Weissbach, L., Boroweic, J.A., Dean, F.B., Murakami, Y., Bullock, P. and Hurwitz, J. (1987) Proc. Natl. Acad. Sci. USA 84, 1834–1838.PubMedCrossRefGoogle Scholar
  184. 184.
    Wold, M.S., Li, J.J. and Kelly, T.J. (1987) Proc. Natl. Acad. Sci. USA 84, 3643–3647.PubMedCrossRefGoogle Scholar
  185. 185.
    Dutta, A. and Stillman, B. (1992) EMBO J. 11, 2189–2199.PubMedGoogle Scholar
  186. 186.
    Höss, A., Moarefi, I., Scheidtmann, K.H., Cisek, L.J., Corden, J.L., Dornreiter, I., Arthur, A. K. and Fanning, E. (1990) J. Virol. 64, 4799–4807.PubMedGoogle Scholar
  187. 187.
    Fotedar, R. and Roberts, J.M. Unpublished observation.Google Scholar
  188. 188.
    Wang, E.H., Friedman, P.N. and Prives, C. (1989) Cell 57, 379–392.PubMedCrossRefGoogle Scholar
  189. 189.
    Amin, A.A., Murakami, Y. and Hurwitz, J. (1994) J. Biol. Chem. 269, 7735–7743.PubMedGoogle Scholar
  190. 190.
    Dutta, A., Ruppert, J. M., Aster, J. C. and Winchester, E. (1993) Nature 365, 79–82.PubMedCrossRefGoogle Scholar
  191. 191.
    Brush, G.S., Anderson, C.W. and Kelly, T.J. (1994) Proc. Natl. Acad. Sci. 91, 12520–12524.PubMedCrossRefGoogle Scholar
  192. 192.
    Pan, Z-Q, Amin, A.A., Gibbs, E., Niu, H. and Hurwitz, J. (1994) Proc. Natl. Acad. Sci. 91, 8343–8347.PubMedCrossRefGoogle Scholar
  193. 193.
    D’Urso, G., Marraccino, R.L., Marshak, D.R. and Roberts, J.M. (1990) Science 250, 786–791.PubMedCrossRefGoogle Scholar
  194. 194.
    Blow, J.J. and Nurse, P. (1990) Cell 62, 855–862.PubMedCrossRefGoogle Scholar
  195. 195.
    Pondaven, P., Meijer, L. and Beach, D. (1990) Genes Dev. 4, 9–17.PubMedCrossRefGoogle Scholar
  196. 196.
    Fang, F. and Newport, J.W. (1991) Cell 66, 731–742.PubMedCrossRefGoogle Scholar
  197. 197.
    Kobayashi, H., Golstein, R., Poon, R., Stewart, E., Gannon J., Minshull, J., Smith R and Hunt, T. (1991) Cold Spring Harbor Symp. Quant. Biol. LVI, 437–447.CrossRefGoogle Scholar
  198. 198.
    Fotedar, A., Cannella, D., Fitzgerald, P., Gupta, S., Doree, M. and Fotedar, R. (1995) In preparation.Google Scholar
  199. 199.
    Nigg, E.A. (1993) Trends Cell Biol. 3, 296–301.PubMedCrossRefGoogle Scholar
  200. 200.
    Nurse, P. (1990). Nature 292, 558–560.CrossRefGoogle Scholar
  201. 201.
    Li, J.J. and Herskowitz, I. (1993) Science 262, 1870–1874.PubMedCrossRefGoogle Scholar
  202. 202.
    Nasheuer, H.-P., Moore, A., Wahl, A.F. and Wang, T.S.-F. (1991) J. Biol. Chem. 266, 7893–7903.PubMedGoogle Scholar
  203. 203.
    Zheng, X-R. Hao, H., Jiang, Y.J. and Lee M.Y.T. (1994) J. Biol. Chem. 269, 24027–24033.Google Scholar
  204. 204.
    Prosperi, E., Scovassi, I., Stivala, L.A. and Bianchi, L. (1994) Exp. Cell Res. 215, 257–262.PubMedCrossRefGoogle Scholar
  205. 205.
    Fotedar, R. Unpublished observations.Google Scholar
  206. 206.
    Adamczewski, J.P., Gannon, J.V. and Hunt, T. (1993) J. Virol. 67, 6551–6557.PubMedGoogle Scholar
  207. 207.
    Henricksen, L.A. and Wold, M.S. (1994) J. Biol. Chem. 269, 24203–24208.PubMedGoogle Scholar
  208. 208.
    Xiong, Y., Zhang, H. and Beach, D. (1993) Genes and Dev. 7, 1572–1583.PubMedCrossRefGoogle Scholar
  209. 209.
    Fotedar, R. and Fotedar, A. Unpublished observations.Google Scholar
  210. 210.
    Li, R., Waga, S., Hannon, G.J., Beach, D. and Stillman, B. (1994) Nature 371, 534–537.PubMedCrossRefGoogle Scholar
  211. 211.
    Michieli, P., Chedid, M., Lin, D., Pierce, J.H., Mercer, W.E. and Givol, D. (1994) Cancer Res. 54, 3391–3395.PubMedGoogle Scholar
  212. 212.
    Li, Y., Jenkins, C.W., Nichols, M.A. and Xiong, Y. (1994) Oncogene 9, 2261–2268.PubMedGoogle Scholar
  213. 213.
    Pagano, M., Theodoras, A.M., Tarn, S.W. and Draetta G. (1994) Genes Dev. 8, 1627–1639.PubMedCrossRefGoogle Scholar
  214. 214.
    Hartwell, L.H. and Weinert, T.A. (1989). Science 246, 629–634.PubMedCrossRefGoogle Scholar
  215. 215.
    Saka, Y. and Yanagida, M. (1993) Cell 74, 383–393.PubMedCrossRefGoogle Scholar
  216. 216.
    Kelly, T.J., Martin, G.S., Forsburg, S.L., Stephen, R.J., Russo, A., and Nurse, P. (1993) Cell 74, 371–382.PubMedCrossRefGoogle Scholar
  217. 217.
    Nurse P. (1994) Cell 79, 547–550.PubMedCrossRefGoogle Scholar
  218. 218.
    Li, J.J. and Deshaies, R.L. (1993) Cell 74, 223–226.PubMedCrossRefGoogle Scholar
  219. 219.
    Brenot-Bosc, F. and Fotedar, R. Unpublished observations.Google Scholar
  220. 220.
    Adachi, Y. and Laemmli, U.K. (1994) EMBO J. 13, 4153–4164.PubMedGoogle Scholar
  221. 221.
    Liu, V.F. and Weaver, D.T. (1993) Mol. Cell. Biol. 13, 7222–7231.PubMedGoogle Scholar
  222. 222.
    Carty, M.P., Zernik-Kobak, M., McGrath, S. and Dixon, K. (1994) EMBO J. 13, 2114–2123.PubMedGoogle Scholar
  223. 223.
    Navas, T.A., Zhou, Z. and Elledge, S.J. (1995) Cell 80, 29–39.PubMedCrossRefGoogle Scholar
  224. 224.
    Francesconi, S., De Recondo, A-M. and Baldacci, G. (1995) Mol. Gen. Genet. In press.Google Scholar

Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • Rati Fotedar
    • 1
  • Arun Fotedar
    • 2
  1. 1.Institut de Biologie Structurale J. -P. EbelGrenoble cedex 1France
  2. 2.La Jolla Institute for Allergy and ImmunologyLa JollaUSA

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