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The Molecular and Cellular Biology of Wound Repair pp 321–335Cite as

Re-epithelialization

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Abstract

Central to the survival of each living organism is the protective outer layer separating the organism from the environment. In all but the simplest forms of life, the barrier is made up of cells that adhere tightly to one another. Such cells, referred to as epithelium or epidermis, generally form single-layered coverings in invertebrates and multilayered coverings in vertebrates. Wounding of this outer barrier layer is potentially lethal to the organism, as body fluids are lost to the environment or destructive environmental elements (chemicals or microorganisms) gain access into the organism. It is to the advantage of a wounded organism to close the rent rapidly, even before underlying tissue repair begins.

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Authors and Affiliations

  1. Department of Dermatology, Yale University, New Haven, Connecticut, 06510, USA

    Kurt S. Stenn

  2. Department of Pathology and Laboratory Medicine, Yale University, New Haven, Connecticut, 06510, USA

    Louis Depalma

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  1. Kurt S. Stenn
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Editors and Affiliations

  1. National Jewish Center for Immunology and Respiratory Medicine, Denver, Colorado, USA

    R. A. F. Clark  & P. M. Henson  & 

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Stenn, K.S., Depalma, L. (1988). Re-epithelialization. In: Clark, R.A.F., Henson, P.M. (eds) The Molecular and Cellular Biology of Wound Repair. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1795-5_14

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