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Cardiac Allograft Rejection pp 3–20Cite as

Histocompatibility Antigens and Transplant Rejection

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Abstract

The specific or adaptive immune system is characterized by the generation and activation of immune cells with an enormous repertoire for the recognition of foreign shapes and by the phenomenon of memory. This sophisticated system of host defense is not found in invertebrates, protochordates, or in some primitive jawless fish. The vertebrate immune system evolved about 450 million years ago in cartilaginous fish, ancestors of present day skates and sharks.1

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Author information

Authors and Affiliations

  1. Cancer Center, Massachusetts General Hospital and Harvard Medical School, USA

    Shiv Pillai M.B.B.S., Ph.D.

Authors
  1. Shiv Pillai M.B.B.S., Ph.D.
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Editor information

Editors and Affiliations

  1. Heart Failure & Transplantation Service, Harvard Medical School, Bigelow 645, 55 Fruit Street, Boston, Massachusetts, 02114, USA

    G William Dec M.D.

  2. Heart Failure/Transplantation Center, Hahnemann University School of Medicine, Broad and Vine Streets, Mail Stop 115, Philadelphia, Pennsylvania, 19102, USA

    Jagat Narula M.D., Ph.D. (Director) (Director)

  3. Department of Cardiology, Hospital Universitari Arnau de Vilanova, Universitat de Lleida, Roure 80, 25198, Lleida, Spain

    Manel Ballester M.D. (Chairman) (Chairman)

  4. Nuclear Medicine Department, Hospital de Sant Pau, Autonomous University of Barcelona, Pare Claret 167, 08025, Barcelona, Spain

    Ignasi Carrio M.D. (Director) (Director)

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© 2001 Springer Science+Business Media New York

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Pillai, S. (2001). Histocompatibility Antigens and Transplant Rejection. In: Dec, G.W., Narula, J., Ballester, M., Carrio, I. (eds) Cardiac Allograft Rejection. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1649-1_1

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  • DOI: https://doi.org/10.1007/978-1-4615-1649-1_1

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5659-2

  • Online ISBN: 978-1-4615-1649-1

  • eBook Packages: Springer Book Archive

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