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Biology of Non-Hodgkin’s Lymphoma

  • Daniel M. Knowles
Chapter
Part of the Cancer Treatment and Research book series (CTAR, volume 104)

Abstract

A relationship between immune deficiency and lymphoid neoplasia has been recognized for more than 30 years.1 2 3Recurring themes among these immunodeficiency-associated malignant lymphomas include origination in and/or involvement of extranodal and unusual anatomic sites, high grade histopathology, B lymphocyte lineage derivation, a frequent association with Epstein-Barr virus infection and often aggressive clinical behavior.4 5 6 Therefore, it should not be too surprising that individuals suffering from HIV-induced immunosuppression also are at significantly increased risk for developing malignant lymphomas that exhibit these same clinical and biological features.

Keywords

Malignant Lymphoma Acquire Immune Deficiency Syndrome Gene Rearrangement Primary Effusion Lymphoma Immunoblastic Lymphoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • Daniel M. Knowles
    • 1
  1. 1.Weill Medical College of Cornell UniversityAmerica

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