Approaches for Evaluation of Immune-Modulating and Anti-Tumor Bioactivities in Chinese Medicinal Herbal Extracts
A recent surge of world attention on research in herbal medicinal plants as a potential fast renewable source for new pharmaceuticals or nutraceuticals has attracted many scientists from diverse disciplines to join this scientific venture. These include molecular biologists, bio-organic chemists, pharmacologists, clinicians and traditional Chinese medical doctors. Hence a trend of true multi-disciplinary collaboration in herbal medicine research is being formed.
KeywordsDendritic Cell Herbal Extract Immature Dendritic Cell Human Dendritic Cell Crude Plant Extract
Unable to display preview. Download preview PDF.
- Kim, K. D., Lee, J. K., Park, S. N., Choe, I. S., Choe, Y.-K. Kim, S. J. Lee, E., and Lim, J.-S. Enhanced antigen-presenting activity and tumour necrosis factor-a-independent activation of dendritic cells following treatment with mycobacterium bovis bacillus Calmette-Guérin. Immunology 97:626–633, 1999.PubMedCrossRefGoogle Scholar
- Koide, S. L., Inaba, K., and Steinman R. M. Interleukin 1 enhanced T-cell-dependent immune responses by amplifying the function of dendritic cells. J. Exp. Med. 165:515–530Google Scholar
- Larsson, M., Messmer, D., Somersan, S., Fonteneau, J.-F., Donahoe, S. M., Lee, M., Dunbar, P. R, Cerundolo, V., Julkunen, I., Nixon, D. F., and Bhardwaj, N. Requirement of mature dendritic cells for efficient activation of influenza A-specific memory CD8+ T cells. J, Immunol. 165:1182–1190, 2000.Google Scholar
- Sallusto, F. and Lanzavecchia, A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocytes/macrophages colony-stimulating factors plus interleukin-4 and down regulated by tumor necrosis factor alpha. J. Exp. Med. 179:1109–1118, 1994.PubMedCrossRefGoogle Scholar