Abstract
In addition to being a source of biochemical energy PPi acts also as a regulator of biochemical reactions and processes. In many reports PPi has been proposed to:
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i.
inhibit or activate some enzymes,
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ii.
influencethe fidelity of protein or nucleic acid synthesis,
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iii.
affect the formation of calcified tissues, cell proliferation and cellular iron transport, and
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iv.
be involved in some pathologic conditions, formation of urinary stones and deposition of calcium pyrophosphate dihydrate crystals into knee joints (pseudogout) being the most studied examples. All these topics are discussed in this chapter.
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© 2001 Springer Science+Business Media New York
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Heinonen, J.K. (2001). Regulatory Roles of PPi. In: Biological Role of Inorganic Pyrophosphate. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1433-6_5
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DOI: https://doi.org/10.1007/978-1-4615-1433-6_5
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-5551-9
Online ISBN: 978-1-4615-1433-6
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