PPi Concentration in Biological Material
Biosynthetic reactions produce large amounts of PPi, as shown by the calculations presented in the chapter 1.2. However, most authors of biochemical textbooks assume that very little of it exists in living cells, because it is hydrolysed immediately by PPase. This assumption is logical, for the removal of PPi prevents the seemingly futile loss of energy which would take place, if the biosynthetic reactions would go backwards in the presence of PPi. However, in the past fifty years PPi has been shown to exist throughout the living world. In this chapter I shall discuss these studies beginning from bacteria and going via lower eukaryotes and plants to animals and humans.
KeywordsChlorophyll Osteoporosis Mold Fluoride Candida
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