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Do Genetic Factors Influence the Dejours Phenomenon?

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Frontiers in Modeling and Control of Breathing

Abstract

Ventilation in response to breathing 100% oxygen is characterized in mammalian species by a decrease in minute ventilation1. This effect, which we will term the “Dejours phenomenon”, is especially evident in the period immediately following exposure to hypoxia. Though the physiologic basis for this phenomenon is not completely understood, it is believed to reflect an acute reduction in peripheral chemoreceptor input, and the magnitude of respiratory depression is considered an index of chemoreceptor drive from the carotid body.

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© 2001 Springer Science+Business Media New York

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Subramanian, S., Han, F., Erokwu, B.O., Dick, T.E., Strohl, K.P. (2001). Do Genetic Factors Influence the Dejours Phenomenon?. In: Poon, CS., Kazemi, H. (eds) Frontiers in Modeling and Control of Breathing. Advances in Experimental Medicine and Biology, vol 499. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1375-9_32

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  • DOI: https://doi.org/10.1007/978-1-4615-1375-9_32

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5522-9

  • Online ISBN: 978-1-4615-1375-9

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