Pathogenicity of Myelin Basic Protein in Anterior Uveitis

Pathogenicity of MBP in uveitis
  • Grazyna Adamus
  • Brad Sugden
  • Maria Manczak
  • Anatol Arendt
  • Paul A. Hargrave


Uveitis is a group of inflammatory eye diseases that may result from infections, malignancies, trauma, or incompletely understood processes that are presumably mediated by the body’s immune system. Uveitis can affect any portion of the uveal track, thus the neighboring tissues such as the retina and vitreous are often affected. Approximately 50% of patients with uveitis have an underlying systemic disease including multiple sclerosis (MS) where central nervous system (CNS) inflammation is associated with the inflammation of the eye. The most common form of uveitis is anterior uveitis (AU), which may precede, occur with, or follow the systemic disease. 1, 2, 3, 4, 5.


Myelin Basic Protein Anterior Uveitis Myelin Basic Protein Peptide Accelerate Onset Underlying Systemic Disease 
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Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • Grazyna Adamus
    • 1
  • Brad Sugden
    • 1
  • Maria Manczak
    • 1
  • Anatol Arendt
    • 2
  • Paul A. Hargrave
    • 2
  1. 1.Neurological Sciences InstituteOregon Health Sciences UniversityPortlandUSA
  2. 2.Department of OphthalmologyUniversity of Florida School of MedicineGainesvilleUSA

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