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Glycobiological Approach to Control of Retinal Degeneration

  • Fumiyuki Uehara
  • Norio Ohba
  • Masayuki Ozawa

Abstract

Medical treatment of degenerative disorders of the central nervous system has been attempted using a number of neurotrophic agents. In the rat retina, direct injection of growth factors or neurotrophic factors into the eye delays photoreceptor degeneration in inherited retinal dystrophy (Faktorovich et al., 1990) and light damage (Faktorovich et al., 1992). Although a combination of different factors enhances the degree of photoreceptor survival (LaVail et al., 1992), the effects of other types of agents should be examined to determine the perfect combination.

Keywords

Photoreceptor Cell Retinal Degeneration Outer Nuclear Layer Maltose Binding Protein Inner Nuclear Layer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • Fumiyuki Uehara
    • 1
  • Norio Ohba
    • 1
  • Masayuki Ozawa
    • 2
  1. 1.Department of OphthalmologyKagoshima University Faculty of MedicineKagoshima-shiJapan
  2. 2.Department of BiochemistryKagoshima University Faculty of MedicineKagoshima-shiJapan

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