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Manufacturing of Gene Therapeutics pp 155–168Cite as

Plasmid DNA Manufacturing

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Abstract

Substantial progress in medicine and biopharmaceutical research may once enable to cure diseases at the level of the specific gene defects rather than at the conventional phenotype level1,2. In addition, the preventive or curative vaccination against pathogenes like bacteria or viruses3,4,5,67; (review: Ref. 8) turns out to be at least working in animal studies. Recent examples for the application of plasmid DNA show that the process of regeneration after surgery can be supported with gene therapeutic techniques1,10.

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Author information

Authors and Affiliations

  1. PlasmidFactory GmbH & Co. KG, Meisenstrasse 96, D-33607, Bielefeld, Germany

    Martin Schleef, Torsten Schmidt & Erwin Flaschel

  2. University of Bielefeld, Postfach 10 01 31, D-33501, Bielefeld, Germany

    Karl Friehs & Erwin Flaschel

Authors
  1. Martin Schleef
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  2. Torsten Schmidt
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  3. Karl Friehs
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  4. Erwin Flaschel
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Editors and Affiliations

  1. Littlebourne, Kent, England

    G. Subramanian

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© 2002 Springer Science+Business Media New York

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Schleef, M., Schmidt, T., Friehs, K., Flaschel, E. (2002). Plasmid DNA Manufacturing. In: Subramanian, G. (eds) Manufacturing of Gene Therapeutics. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1353-7_8

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  • DOI: https://doi.org/10.1007/978-1-4615-1353-7_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5512-0

  • Online ISBN: 978-1-4615-1353-7

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