Intractable Epilepsy in Adults

  • Ilo E. Leppik
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 497)


Most patients with epilepsy can achieve complete control of seizures with medication. Nevertheless, a substantial number develop intractable epilepsy—and all of the attendant medical and psychosocial difficulties associated with uncontrolled seizures. Various estimates have placed the number of persons continuing to have seizures in spite of medical treatment at 17% to 31% of the population of persons with epilepsy.14,13 In this chapter, three areas will be reviewed: 1) evaluation of a person with uncontrolled seizures; 2) definition of “intractable” epilepsy; and 3) predictors of intractability.


Temporal Lobe Epilepsy Seizure Type Intractable Epilepsy Sodium Valproate Complex Partial Seizure 
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Copyright information

© Springer Science+Business Media New York 2002

Authors and Affiliations

  • Ilo E. Leppik
    • 1
  1. 1.Clinical Professor of Neurology and PharmacyUniversity of Minnesota Director of Pharmacology,Research MINCEP Epilepsy Care P.A.Minnesota

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